Reactome | ACSF2 [mitochondrial matrix]

ACSF2 [mitochondrial matrix]

Stable Identifier

R-HSA-5696005

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Acyl-CoA synthetase family member 2, mitochondrial ecNumber6.2.1.-/ecNumber, ACSF2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96CM8 ACSF2

Gene Names

ACSF2, UNQ493/PRO1009

Chain

transit peptide:1-41, chain:42-615

Reference Genes

BioGPS Gene:80221 ACSF2

COSMIC (genes):ACSF2 ACSF2

CTD Gene:80221 ACSF2

dbSNP Gene:80221 ACSF2

ENSEMBL:ENSG00000167107 ACSF2

HGNC:26101 ACSF2

KEGG:hsa:80221 ACSF2

Monarch:80221 ACSF2

NCBI Gene:80221 ACSF2

OMIM:610465 ACSF2

UCSC:Q96CM8 ACSF2

Reference Transcript

Other Identifiers

11719035_a_at

16835816

218844_PM_at

218844_at

3726407

3726408

3726411

3726420

3726421

3726422

3726423

3726424

3726425

3726426

3726427

3726428

3726429

3726430

3726431

3726432

3726433

3726434

3726435

3726436

3726437

3726438

3726440

3726444

3726445

3726446

3726447

3726448

3726449

3726450

3726451

3726452

3726453

3726454

3726455

3726456

3726457

3726458

3726459

3726460

3726461

3726462

3726464

48011_at

60079_s_at

8008321

80221

A_23_P4190

GE83105

GO:0000166

GO:0001676

GO:0003824

GO:0004467

GO:0005515

GO:0005524

GO:0005739

GO:0005759

GO:0006629

GO:0006631

GO:0006637

GO:0006790

GO:0016874

GO:0031956

GO:0043226

GO:0055086

GO:0140657

GO:1901135

HMNXSV003036815

HMNXSV003053577

PH_hs_0032521

g13376740_3p_at

Inferred To

ACSF2 [mitochondrial matrix] (Bos taurus)

ACSF2 [mitochondrial matrix] (Canis familiaris)

ACSF2 [mitochondrial matrix] (Danio rerio)

ACSF2 [mitochondrial matrix] (Gallus gallus)

ACSF2 [mitochondrial matrix] (Mus musculus)

ACSF2 [mitochondrial matrix] (Rattus norvegicus)

ACSF2 [mitochondrial matrix] (Sus scrofa)

acs-1 [mitochondrial matrix] (Caenorhabditis elegans)

acsf2 [mitochondrial matrix] (Xenopus tropicalis)

Acsf2 [mitochondrial matrix] (Drosophila melanogaster)

Cross References

OpenTargets

ENSG00000167107

ENSEMBL

ENST00000427954, ENSP00000300441, ENSP00000421884, ENST00000502667, ENSP00000401831, ENST00000300441

HPA

ENSG00000167107-ACSF2

PRO

Q96CM8

Pharos - Targets

Q96CM8

GlyGen

Q96CM8

HMDB Protein

HMDBP11002

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15041 AR6P1			0.83	8
UniProt:Q96DZ9 CKLF5			0.742	5
UniProt:O75208 COQ9	1	COQ9 [mitochondrial inner membrane] (R-HSA-8932994)	0.666	4
UniProt:Q6RW13 AGTRAP	2	AGTRAP(1-159)-BRAF(288-545) fusion [cytosol] (R-HSA-6802262) AGTRAP(1-159)-p-BRAF(288-545) fusion [cytosol] (R-HSA-6802511)	0.666	4
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3
UniProt:Q6Q788 APOA5	4	APOA5 [endoplasmic reticulum lumen] (R-HSA-8956716) p-APOA5 [endoplasmic reticulum lumen] (R-HSA-8956979) APOA5 [extracellular region] (R-HSA-174608) APOA5 [cytosol] (R-HSA-6784664)	0.556	3
UniProt:P02654 APOC1	1	APOC1 [extracellular region] (R-HSA-8855541)	0.556	3
UniProt:Q5XKP0 MICOS13	1	MIC13 (QIL1) [mitochondrial inner membrane] (R-HSA-8949561)	0.556	3
UniProt:Q8IZV5 RDH10	1	RDH10 [endoplasmic reticulum membrane] (R-HSA-2454090)	0.556	3
UniProt:O43761 SNG3			0.556	3
UniProt:Q9HC62 SENP2	1	SENP2 [nucleoplasm] (R-HSA-2984298)	0.556	3
UniProt:Q8TDT2 GP152			0.556	3
UniProt:Q6NTF9-3 Q6NTF93			0.556	3
UniProt:Q96PQ1 SIGLEC12	1	SIGLEC12 [plasma membrane] (R-HSA-197729)	0.556	3
UniProt:Q8IUN9 CLEC10A	1	CLEC10A [plasma membrane] (R-HSA-1472863)	0.556	3
UniProt:Q9Y371 SHLB1			0.556	3
UniProt:Q8IYJ2-2 C10ORF67			0.556	3
UniProt:Q6ZPD8 DGAT2L6	1	DGAT2L6 [endoplasmic reticulum membrane] (R-HSA-8848588)	0.556	3
UniProt:Q96DZ9-2 CMTM5			0.556	3
UniProt:O43889 CREB3	7	CREB3 [endoplasmic reticulum membrane] (R-HSA-8874165) CREB3(292-371) [Golgi membrane] (R-HSA-8874173) CREB3 [Golgi membrane] (R-HSA-8874123) CREB3(257-291) [Golgi membrane] (R-HSA-8874207) CREB3(1-291) [Golgi membrane] (R-HSA-8874181) CREB3(1-256) [cytosol] (R-HSA-8874135) CREB3(1-256) [nucleoplasm] (R-HSA-8874190)	0.553	2
UniProt:P52815 MRPL12	2	MRPL12 [mitochondrial inner membrane] (R-HSA-5368256) MRPL12 [mitochondrial matrix] (R-HSA-9839674)	0.527	2

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