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Go!
INHA [extracellular region]
Stable Identifier
R-HSA-1449702
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Inhibin alpha chain, INHA_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Peptide hormone biosynthesis (Homo sapiens)
Glycoprotein hormones (Homo sapiens)
Follitropin is a heterodimer (Homo sapiens)
INHIB [extracellular region] (Homo sapiens)
INHA [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by Activin (Homo sapiens)
Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Homo sapiens)
INHIBIN-A:TGFBR3:ACVR2A [plasma membrane] (Homo sapiens)
INHIBIN-A:TGFBR3 [plasma membrane] (Homo sapiens)
INHIBIN-A [extracellular region] (Homo sapiens)
INHA [extracellular region] (Homo sapiens)
Activin AB,B binds Activin Receptor ACVR2A,B:ACVR1C (Homo sapiens)
INHIBIN-A:TGFBR3:ACVR2A [plasma membrane] (Homo sapiens)
INHIBIN-A:TGFBR3 [plasma membrane] (Homo sapiens)
INHIBIN-A [extracellular region] (Homo sapiens)
INHA [extracellular region] (Homo sapiens)
Signaling by BMP (Homo sapiens)
BMP2 binds to the receptor complex (Homo sapiens)
INHIBIN-A:TGFBR3:ACVR2A [plasma membrane] (Homo sapiens)
INHIBIN-A:TGFBR3 [plasma membrane] (Homo sapiens)
INHIBIN-A [extracellular region] (Homo sapiens)
INHA [extracellular region] (Homo sapiens)
Signaling by TGFBR3 (Homo sapiens)
TGFBR3 regulates activin signaling (Homo sapiens)
Inhibin-A binding to TGFBR3 (Homo sapiens)
INHIBIN-A [extracellular region] (Homo sapiens)
INHA [extracellular region] (Homo sapiens)
INHIBIN-A:TGFBR3 [plasma membrane] (Homo sapiens)
INHIBIN-A [extracellular region] (Homo sapiens)
INHA [extracellular region] (Homo sapiens)
InhibinA-TGFBR3 binding to ACVR2A (Homo sapiens)
INHIBIN-A:TGFBR3 [plasma membrane] (Homo sapiens)
INHIBIN-A [extracellular region] (Homo sapiens)
INHA [extracellular region] (Homo sapiens)
INHIBIN-A:TGFBR3:ACVR2A [plasma membrane] (Homo sapiens)
INHIBIN-A:TGFBR3 [plasma membrane] (Homo sapiens)
INHIBIN-A [extracellular region] (Homo sapiens)
INHA [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P05111 INHA
Gene Names
INHA
Chain
signal peptide:1-18, propeptide:19-61, propeptide:62-232, chain:233-366
Reference Genes
BioGPS Gene:3623 INHA
COSMIC (genes):INHA INHA
CTD Gene:3623 INHA
dbSNP Gene:3623 INHA
ENSEMBL:ENSG00000123999 INHA
ENSEMBL_homo_sapiens_GENE:ENSG00000123999.5 INHA
HGNC:6065 INHA
KEGG Gene (Homo sapiens):3623 INHA
Monarch:3623 INHA
NCBI Gene:3623 INHA
OMIM:147380 INHA
UCSC:P05111 INHA
Reference Transcript
RefSeq:NM_002191.3 INHA
Other Identifiers
11723157_at
16891403
210141_PM_s_at
210141_s_at
2528700
2528701
2528702
2528705
2528706
255_s_at
3623
38544_at
8048639
A_23_P51039
GE57822
GO:0001501
GO:0001541
GO:0001750
GO:0001917
GO:0002376
GO:0005102
GO:0005125
GO:0005179
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0005929
GO:0007165
GO:0007166
GO:0007267
GO:0008083
GO:0008584
GO:0022414
GO:0023052
GO:0030154
GO:0030218
GO:0032689
GO:0034673
GO:0034711
GO:0042127
GO:0042326
GO:0042541
GO:0043025
GO:0043226
GO:0043512
GO:0043513
GO:0044877
GO:0045578
GO:0045650
GO:0045786
GO:0046881
GO:0046882
GO:0048018
GO:0048856
GO:0050886
GO:0051726
GO:0098772
HMNXSV003037080
ILMN_1756443
M13981_at
PH_hs_0024699
TC02001332.hg
X04445_rna1_s_at
g186410_3p_s_at
Participates
as a component of
INHIB [extracellular region] (Homo sapiens)
INHIBIN-A [extracellular region] (Homo sapiens)
Inferred To
mav [extracellular region]
(Drosophila melanogaster)
inha [extracellular region]
(Xenopus tropicalis)
Inha [extracellular region]
(Mus musculus)
Inha [extracellular region]
(Rattus norvegicus)
Homologues of INHA [extracellular region]
(Drosophila melanogaster)
INHA [extracellular region]
(Bos taurus)
INHA [extracellular region]
(Canis familiaris)
INHA [extracellular region]
(Gallus gallus)
INHA [extracellular region]
(Sus scrofa)
dpp [extracellular region]
(Drosophila melanogaster)
Cross References
RefSeq
NP_002182.1
OpenTargets
ENSG00000123999
HPA
ENSG00000123999-INHA
GeneCards
P05111
Ensembl
ENST00000243786
,
ENSP00000243786
,
ENSG00000123999
PRO
P05111
Pharos - Targets
P05111
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8IUQ4 SIAH1
1
SIAH1 [cytosol]
(R-HSA-374563)
0.556
3
UniProt:P11021 HSPA5
6
HSPA5 [extracellular region]
(R-HSA-351322)
HSPA5 [endoplasmic reticulum lumen]
(R-HSA-387190)
HSPA5 [endoplasmic reticulum membrane]
(R-HSA-351315)
HSPA5 [cytosol]
(R-HSA-5252115)
HSPA5 [nucleoplasm]
(R-HSA-5252042)
HSPA5 [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985498)
0.527
2
UniProt:P27797 CALR
6
CALR [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985502)
CALR [extracellular region]
(R-HSA-2197641)
CALR [endocytic vesicle lumen]
(R-HSA-2239448)
CALR [endoplasmic reticulum lumen]
(R-HSA-195905)
CALR [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863866)
CALR [phagocytic vesicle membrane]
(R-HSA-1236879)
0.527
2
UniProt:P30101 PDIA3
3
PDIA3 [phagocytic vesicle]
(R-HSA-1236870)
PDIA3 [recycling endosome membrane]
(R-HSA-8863849)
PDIA3 [endoplasmic reticulum lumen]
(R-HSA-901028)
0.527
2
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