Reactome | PPM1B [cytosol]

Stable Identifier

R-HSA-1169375

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

PP2CB, Protein phosphatase 1B, PPM1B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O75688 PPM1B

Gene Names

PPM1B, PP2CB

Chain

initiator methionine:1, chain:2-479

Reference Genes

COSMIC (genes):PPM1B PPM1B

dbSNP Gene:5495 PPM1B

ENSEMBL:ENSG00000138032 PPM1B

Participates

as a component of

as an input of

Other forms of this molecule

Inferred To

alph [cytosol] (Drosophila melanogaster)

tap-1 [cytosol] (Caenorhabditis elegans)

Nil [cytosol] (Drosophila melanogaster)

PPM1B [cytosol] (Bos taurus)

PPM1B [cytosol] (Caenorhabditis elegans)

PPM1B [cytosol] (Mus musculus)

PPM1B [cytosol] (Rattus norvegicus)

PPM1B [cytosol] (Sus scrofa)

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32121 ARRB2	3	ARRB2 [cytosol] (R-HSA-416464) PolyUb-ARRB2 [cytosol] (R-HSA-6783000) ARRB2 [endocytic vesicle membrane] (R-HSA-9910881)	0.604	4
UniProt:P05161 ISG15	4	ISG15 [cytosol] (R-HSA-936552) K168-PCNA-G157-ISG15 [nucleoplasm] (R-HSA-5653744) K164-PCNA-G157-ISG15 [nucleoplasm] (R-HSA-5653745) ISG15 [nucleoplasm] (R-HSA-5653665)	0.558	2
UniProt:P21860 ERBB3			0.553	2
UniProt:Q14392 LRC32			0.527	2
UniProt:P15151 PVR	1	PVR [plasma membrane] (R-HSA-420600)	0.527	3
UniProt:Q86XA9 HTR5A			0.527	2
UniProt:Q9H293 IL25	1	IL25 [extracellular region] (R-HSA-447101)	0.527	2
UniProt:Q49MI3 CERKL			0.527	3
UniProt:Q9BV44 THUM3			0.527	3
UniProt:Q9BUH6 PAXX			0.527	2
UniProt:P49407 ARRB1	6	ARRB1 [cytosol] (R-HSA-264470) PolyUb-ARRB1 [cytosol] (R-HSA-6783186) ARRB1 [endocytic vesicle membrane] (R-HSA-9910882) ARRB1 [lysosomal membrane] (R-HSA-432701) ARRB1 [Golgi membrane] (R-HSA-350831) ARRB1 [cytoplasmic vesicle membrane] (R-HSA-351187)	0.499	4
UniProt:Q8IUH3 RBM45			0.462	2

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