Reactome | EPOR [plasma membrane]

EPOR [plasma membrane]

Stable Identifier

R-HSA-1168347

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Erythropoietin receptor, EPOR_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P19235 EPOR

Gene Names

EPOR

Chain

signal peptide:1-24, chain:25-508

Reference Genes

BioGPS Gene:2057 EPOR

COSMIC - genes:EPOR EPOR

CTD Gene:2057 EPOR

dbSNP Gene:2057 EPOR

ENSEMBL:ENSG00000187266 EPOR

HGNC:3416 EPOR

KEGG:hsa:2057 EPOR

Monarch:2057 EPOR

NCBI Gene:2057 EPOR

OMIM:133171 EPOR

UCSC:P19235 EPOR

Reference Transcript

RefSeq:NM_000121.4 EPOR

Other Identifiers

1087_at

11740081_a_at

16868928

2057

209962_PM_at

209962_at

209963_PM_s_at

209963_s_at

215054_3p_at

215054_PM_at

215054_at

31681_at

37986_PM_at

37986_at

3850860

3850861

3850862

3850863

3850864

3850869

3850870

3850871

3850872

3850873

3850874

3850875

3850876

3850877

3850878

3850879

3850881

3850882

3850883

396_3p_f_at

396_PM_f_at

396_f_at

4876922C_3p_at

8034217

A_23_P367899

A_23_P381954

A_24_P914376

GE58209

GO:0004888

GO:0004896

GO:0004900

GO:0005515

GO:0005576

GO:0005886

GO:0007165

GO:0007420

GO:0007507

GO:0009897

GO:0016020

GO:0016607

GO:0019221

GO:0030163

GO:0038162

GO:0042802

GO:0043161

GO:0046697

GO:0048856

HMNXSV003015443

Hs.89548.1.S1_3p_s_at

ILMN_2168347

M60459_at

PH_hs_0007355

TC19002335.hg

TC19002676.hg

X97671cds_3p_s_at

g182200_3p_at

g182200_3p_x_at

p26738

Participates

as a component of

Other forms of this molecule

p-8Y-EPOR [plasma membrane]

Inferred To

Epor [plasma membrane] (Mus musculus)

Epor [plasma membrane] (Rattus norvegicus)

Ghost homologue of EPOR [plasma membrane] (Gallus gallus)

epor [plasma membrane] (Danio rerio)

epor [plasma membrane] (Xenopus tropicalis)

EPOR [plasma membrane] (Bos taurus)

EPOR [plasma membrane] (Canis familiaris)

EPOR [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_000112.1

Guide to Pharmacology - Targets

1718

OpenTargets

ENSG00000187266

ENSEMBL

ENST00000222139, ENSG00000187266, ENST00000592375, ENSP00000467809, ENSP00000222139

ZINC - Substances

EPOR_HUMAN

ZINC target

P19235

PRO

P19235

GlyGen

P19235

PDB

6MOF, 8VVM, 2MV6, 8VVO, 6MOE, 6MOL, 4Y5V, 6E2Q, 6MOJ, 6MOK, 4Y5X, 1EER, 6MOH, 1ERN, 8VUI, 6I4X, 1EBP, 4Y5Y, 1EBA, 6MOI, 2JIX, 1CN4

HPA

ENSG00000187266-EPOR

GeneCards

EPOR

Pharos - Targets

P19235

Orphanet

EPOR

ZINC - Predictions - Purchasable

EPOR_HUMAN

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29350 PTPN6	5	PTPN6 [cytosol] (R-HSA-197938) PTPN6 [nucleoplasm] (R-HSA-9008911) PTPN6 [tertiary granule lumen] (R-HSA-6800952) PTPN6 [extracellular region] (R-HSA-6806315) PTPN6 [specific granule lumen] (R-HSA-6799641)	0.8	11
UniProt:P01588 EPO	1	EPO [extracellular region] (R-HSA-379001)	0.609	3
UniProt:P18031 PTPN1	2	PTPN1 [endosome membrane] (R-HSA-9815895) PTPN1 [cytosol] (R-HSA-210625)	0.602	3
UniProt:Q92835 INPP5D	2	INPP5D [cytosol] (R-HSA-197940) p-Y-INPP5D [cytosol] (R-HSA-9680730)	0.547	2