Reactome | EPOR [plasma membrane]

EPOR [plasma membrane]

Stable Identifier

R-HSA-1168347

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Erythropoietin receptor, EPOR_HUMAN

Icon

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P19235 EPOR

Gene Names

EPOR

Chain

signal peptide:1-24, chain:25-508

Reference Genes

BioGPS Gene:2057 EPOR

COSMIC (genes):EPOR EPOR

CTD Gene:2057 EPOR

dbSNP Gene:2057 EPOR

ENSEMBL:ENSG00000187266.14 EPOR

HGNC:3416 EPOR

KEGG Gene (Homo sapiens):2057 EPOR

Monarch:2057 EPOR

NCBI Gene:2057 EPOR

OMIM:133171 EPOR

UCSC:P19235 EPOR

Reference Transcript

RefSeq:NM_000121.3 EPOR

Other Identifiers

1087_at

11740081_a_at

16868928

2057

209962_PM_at

209962_at

209963_PM_s_at

209963_s_at

215054_3p_at

215054_PM_at

215054_at

37986_PM_at

37986_at

3850860

3850861

3850862

3850863

3850864

3850870

3850872

3850874

3850875

3850876

3850879

3850882

3850883

396_3p_f_at

396_PM_f_at

396_f_at

4876922C_3p_at

8034217

A_23_P367899

A_23_P381954

GE58209

GO:0002376

GO:0004888

GO:0004896

GO:0004900

GO:0005515

GO:0005576

GO:0005634

GO:0005654

GO:0005886

GO:0007165

GO:0007420

GO:0007507

GO:0008284

GO:0009897

GO:0016020

GO:0016021

GO:0016607

GO:0019221

GO:0022414

GO:0023052

GO:0030097

GO:0038162

GO:0042802

GO:0043226

GO:0046697

GO:0048856

GO:0060089

HMNXSV003015443

Hs.89548.1.S1_3p_s_at

ILMN_2168347

M60459_at

PH_hs_0007355

TC19002335.hg

TC19002676.hg

X97671cds_3p_s_at

g182200_3p_at

g182200_3p_x_at

Participates

as a component of

Other forms of this molecule

p-8Y-EPOR [plasma membrane]

Inferred To

Epor [plasma membrane] (Mus musculus)

Epor [plasma membrane] (Rattus norvegicus)

Ghost homologue of EPOR [plasma membrane] (Drosophila melanogaster)

Ghost homologue of EPOR [plasma membrane] (Xenopus tropicalis)

EPOR [plasma membrane] (Bos taurus)

EPOR [plasma membrane] (Canis familiaris)

EPOR [plasma membrane] (Danio rerio)

EPOR [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_000112.1

Guide to Pharmacology - Targets

1718

OpenTargets

ENSG00000187266

ZINC - Substances

EPOR_HUMAN

ZINC target

P19235

PRO

P19235

PDB

6MOL, 6MOI, 6E2Q, 1EBP, 2JIX, 1EER, 4Y5Y, 6MOH, 1CN4, 6MOJ, 1EBA, 6MOK, 1ERN, 4Y5V, 6MOF, 4Y5X, 6MOE, 2MV6

HPA

ENSG00000187266-EPOR

GeneCards

P19235

Ensembl

ENSG00000187266, ENSP00000467809, ENSP00000222139, ENST00000222139, ENST00000592375

Pharos - Targets

P19235

Orphanet

15987

ZINC - Predictions - Purchasable

EPOR_HUMAN

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29350 PTPN6	5	PTPN6 [specific granule lumen] (R-HSA-6799641) PTPN6 [extracellular region] (R-HSA-6806315) PTPN6 [tertiary granule lumen] (R-HSA-6800952) PTPN6 [nucleoplasm] (R-HSA-9008911) PTPN6 [cytosol] (R-HSA-197938)	0.8	11
UniProt:P01588 EPO	1	EPO [extracellular region] (R-HSA-379001)	0.609	3
UniProt:P18031 PTPN1	2	PTPN1 [cytosol] (R-HSA-210625) PTPN1 [endosome membrane] (R-HSA-9815895)	0.602	3
UniProt:Q92835 INPP5D	2	p-Y-INPP5D [cytosol] (R-HSA-9680730) INPP5D [cytosol] (R-HSA-197940)	0.547	2