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GAG-POL Polyprotein (P04585) [extracellular region]
Stable Identifier
R-HIV-3139031
Type
Protein [EntityWithAccessionedSequence]
Species
Human immunodeficiency virus 1
Compartment
extracellular region
GO Cellular Component
host cell cytosol
(0044164)
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Immature HIV virion [extracellular region] (Homo sapiens)
GAG-POL Polyprotein (P04585) [extracellular region] (Human immunodeficiency virus 1)
Maturation of HIV Virion (Homo sapiens)
Immature HIV virion [extracellular region] (Homo sapiens)
GAG-POL Polyprotein (P04585) [extracellular region] (Human immunodeficiency virus 1)
GAG-POL Polyprotein (P04585) [extracellular region] (Human immunodeficiency virus 1)
Protease:Protease inhibitors [extracellular region] (Human immunodeficiency virus 1)
GAG-POL Polyprotein (P04585) [extracellular region] (Human immunodeficiency virus 1)
Protease binds protease inhibitors (Homo sapiens)
GAG-POL Polyprotein (P04585) [extracellular region] (Human immunodeficiency virus 1)
Protease:Protease inhibitors [extracellular region] (Human immunodeficiency virus 1)
GAG-POL Polyprotein (P04585) [extracellular region] (Human immunodeficiency virus 1)
External Reference Information
External Reference
UniProt:P04585 gag-pol
Gene Names
gag-pol
Chain
initiator methionine:, chain:2-1435, chain:2-132, chain:133-363, peptide:364-377, chain:378-432, peptide:433-440, chain:441-488, chain:489-587, chain:588-1147, chain:588-1027, chain:1028-1147, chain:1148-1435
Reference Genes
BioGPS Gene:155348 gag-pol
KEGG Gene (Hepatitis C Virus):155348 gag-pol
Monarch:155348 gag-pol
NCBI Gene:155348 gag-pol
Reference Transcript
RefSeq:NC_001802.1 gag-pol
Participates
as a component of
Immature HIV virion [extracellular region] (Homo sapiens)
Protease:Protease inhibitors [extracellular region] (Human immunodeficiency virus 1)
as an input of
Protease binds protease inhibitors (Homo sapiens)
Other forms of this molecule
GAG-POL Polyprotein (P04585) [plasma membrane]
MA (P04585) protein [nucleoplasm]
IN (Integrase) (P04585) protein [nucleoplasm]
p6 (P04585) [nucleoplasm]
NC (P04585) protein [cytosol]
CA (P04585) protein [cytosol]
PR (Protease) (P04585) protein [cytosol]
p6 (P04585) protein [extracellular region]
p51 (RT) [extracellular region]
Reverse transcriptase/ribonuclease H [extracellular region]
CA (P04585) protein [extracellular region]
PR (Protease) (P04585) protein [extracellular region]
IN (Integrase) (P04585) protein [extracellular region]
MA (P04585) protein [extracellular region]
NC (P04585) protein [extracellular region]
Reverse transcriptase/ribonuclease H [cytosol]
p51 (RT) [cytosol]
IN (Integrase) (P04585) protein [cytosol]
p6 (P04585) protein [cytosol]
MA (P04585) protein [cytosol]
Cross References
RefSeq
NP_057849.4
IntEnz
3.4.23.16
PRO
P04585
PDB
1S1V
,
1LWE
,
1O1W
,
1A30
,
3KT2
,
6SKN
,
3M8P
,
1FB7
,
7XJ4
,
1JKH
,
5HRR
,
1FKP
,
6UIT
,
1C0U
,
6OTZ
,
3C6T
,
1JLA
,
1S1X
,
1ODW
,
6EX9
,
6SLQ
,
3KJV
,
6DJ7
,
1BWA
,
3TAM
,
2YNG
,
6WAZ
,
1LWF
,
6GL1
,
1TKX
,
2YNH
,
6OR7
,
1TAM
,
6UJX
,
2HNY
,
1RT3
,
3I0R
,
1QBU
,
1HIV
,
2NPH
,
3KT5
,
1BV7
,
6BSG
,
3M8Q
,
7XJ5
,
5EU7
,
3LP0
,
5HRS
,
2HND
,
1C1B
,
7XJ7
,
6J1V
,
5T82
,
1JLB
,
1RTD
,
1G6L
,
3C6U
,
3KK1
,
1ESK
,
3N3I
,
1EX4
,
6SLU
,
1ODY
,
1TKZ
,
4KSE
,
2YNI
,
6UJY
,
1BV9
,
2HNZ
,
5K14
,
3I0S
,
4KV8
,
3DLE
,
3AO2
,
1EXQ
,
3LP1
,
6SMU
,
6BSH
,
2WOM
,
1EP4
,
6J1W
,
3DI6
,
1C1C
,
8FCC
,
1JLC
,
1RT7
,
3FFI
,
6WB1
,
4QLH
,
3KK2
,
1RT4
,
6VPZ
,
1TL1
,
2OPP
,
6UJZ
,
3NBP
,
1RTJ
,
3DLG
,
1DTQ
,
3PHV
,
5KAO
,
6BSI
,
2WON
,
3LP2
,
8FCD
,
3DM2
,
3LAK
,
6P1I
,
6BSJ
,
3E01
,
6DIF
,
1JLE
,
6BJ2
,
6DV0
,
3KK3
,
6PYL
,
4Q1W
,
6UK0
,
6VQ2
,
5DGU
,
1TL3
,
2OPQ
,
1DTT
,
1HVH
,
1REV
,
3MEC
,
3MED
,
7R7V
,
1BVG
,
8FCE
,
3LAL
,
1JLF
,
1RTH
,
1VRT
,
6BJ3
,
1BWB
,
3QIN
,
6P1X
,
1C0T
,
6DIL
,
4Q5M
,
6DV4
,
4U1H
,
1FK9
,
3DMJ
,
3DOK
,
6WPF
,
4U7Q
,
1S1W
,
4Q1X
,
5J2M
,
4Q1Y
,
6WPH
,
4U7V
,
6P2G
,
5TC2
,
1LV1
,
5DGW
,
2OPR
,
6E7J
,
5VZ6
,
6VQD
,
1HWR
,
4I7F
,
4B3O
,
1JLQ
,
5XOS
,
1JLG
,
3MEE
,
3LAM
,
1VRU
,
1QBS
,
5IM7
,
3DYA
,
7R7X
,
3QIO
,
6DJ1
,
4U1I
,
1HVR
,
3DOL
,
5J2N
,
6E9A
,
1E6J
,
2WHH
,
5J2P
,
1S1T
,
2OPS
,
6WPJ
,
3DOX
,
1HXB
,
1RT2
,
6SKK
,
6VQE
,
5HRN
,
1LW2
,
5XOT
,
1RT1
,
4B3P
,
3DRP
,
1FKO
,
4B3Q
,
3DRR
,
6UIR
,
1NCP
,
7R80
,
1LW0
,
3MEG
,
2RKI
,
3LAN
,
1BVE
,
1DMP
,
1RT6
,
6VQY
,
7SLR
,
1T05
,
3QIP
,
6DJ2
,
3T19
,
4U1J
,
2KOD
,
5YRS
,
1QBR
,
2YNF
,
5J2Q
,
1S1U
,
3T1A
,
1LWC
,
1TKT
,
1QBT
,
6SKM
,
4NCG
,
1KLM
,
1RTI
,
2RF2
,
7XIU
,
5HRP
,
6UIS
,
6EWA
,
3DRS
,
6VQZ
,
7SLS
,
6DJ5
,
1RT5
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04585 gag-pol
20
GAG-POL Polyprotein (P04585) [extracellular region]
(R-HIV-3139031)
GAG-POL Polyprotein (P04585) [plasma membrane]
(R-HIV-3076336)
MA (P04585) protein [nucleoplasm]
(R-HIV-3006250)
IN (Integrase) (P04585) protein [nucleoplasm]
(R-HIV-175288)
p6 (P04585) [nucleoplasm]
(R-HIV-175300)
NC (P04585) protein [cytosol]
(R-HIV-3006251)
CA (P04585) protein [cytosol]
(R-HIV-3006247)
PR (Protease) (P04585) protein [cytosol]
(R-HIV-175182)
p6 (P04585) protein [extracellular region]
(R-HIV-175560)
p51 (RT) [extracellular region]
(R-HIV-175342)
Reverse transcriptase/ribonuclease H [extracellular region]
(R-HIV-175316)
CA (P04585) protein [extracellular region]
(R-HIV-175492)
PR (Protease) (P04585) protein [extracellular region]
(R-HIV-173391)
IN (Integrase) (P04585) protein [extracellular region]
(R-HIV-175406)
MA (P04585) protein [extracellular region]
(R-HIV-175359)
NC (P04585) protein [extracellular region]
(R-HIV-3006248)
Reverse transcriptase/ribonuclease H [cytosol]
(R-HIV-173370)
p51 (RT) [cytosol]
(R-HIV-173834)
IN (Integrase) (P04585) protein [cytosol]
(R-HIV-173387)
p6 (P04585) protein [cytosol]
(R-HIV-3072746)
0.73
29
UniProt:P03366 POL
0.623
2
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