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GAG-POL Polyprotein (P04585) [plasma membrane]
Stable Identifier
R-HIV-3076336
Type
Protein [EntityWithAccessionedSequence]
Species
Human immunodeficiency virus 1
Compartment
plasma membrane
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Assembly Of The HIV Virion (Homo sapiens)
Packaging of HIV virion on the host cell plasma membrane (Homo sapiens)
Assembling HIV virion [plasma membrane] (Homo sapiens)
GAG-POL Polyprotein (P04585) [plasma membrane] (Human immunodeficiency virus 1)
GAG-POL Polyprotein (P04585) [plasma membrane] (Human immunodeficiency virus 1)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Assembling HIV virion [plasma membrane] (Homo sapiens)
GAG-POL Polyprotein (P04585) [plasma membrane] (Human immunodeficiency virus 1)
External Reference Information
External Reference
UniProt:P04585 gag-pol
Gene Names
gag-pol
Chain
initiator methionine:1, chain:2-1435, chain:2-132, chain:133-363, peptide:364-377, chain:378-432, peptide:433-440, chain:441-488, chain:489-587, chain:588-1147, chain:588-1027, chain:1028-1147, chain:1148-1435
Reference Genes
BioGPS Gene:155348 gag-pol
KEGG:vg:155348 gag-pol
Monarch:155348 gag-pol
NCBI Gene:155348 gag-pol
UCSC:P04585 gag-pol
Reference Transcript
RefSeq:NC_001802.1 env
Participates
as a component of
Assembling HIV virion [plasma membrane] (Homo sapiens)
as an input of
Packaging of HIV virion on the host cell plasma membrane (Homo sapiens)
Other forms of this molecule
MA (P04585) protein [cytosol]
p6 (P04585) protein [cytosol]
IN (Integrase) (P04585) protein [cytosol]
p51 (RT) [cytosol]
Reverse transcriptase/ribonuclease H [cytosol]
NC (P04585) protein [extracellular region]
MA (P04585) protein [extracellular region]
IN (Integrase) (P04585) protein [extracellular region]
PR (Protease) (P04585) protein [extracellular region]
CA (P04585) protein [extracellular region]
Reverse transcriptase/ribonuclease H [extracellular region]
p51 (RT) [extracellular region]
p6 (P04585) protein [extracellular region]
PR (Protease) (P04585) protein [cytosol]
CA (P04585) protein [cytosol]
NC (P04585) protein [cytosol]
p6 (P04585) [nucleoplasm]
IN (Integrase) (P04585) protein [nucleoplasm]
MA (P04585) protein [nucleoplasm]
GAG-POL Polyprotein (P04585) [extracellular region]
Cross References
RefSeq
NP_057849.4
IntEnz
3.4.23.16
PRO
P04585
PDB
3LP2
,
1DTT
,
1S1W
,
7R7X
,
4U7V
,
7XJ4
,
7XIU
,
1RT3
,
8F5A
,
5HRS
,
7SLR
,
3NBP
,
1FB7
,
2HNY
,
1O1W
,
5DGW
,
4Q1W
,
1HWR
,
3QIN
,
6SLQ
,
3DM2
,
1JLG
,
6DIF
,
8TCK
,
6DIL
,
2OPR
,
6VPZ
,
4U1J
,
1QBR
,
1FKO
,
6SKK
,
3LAM
,
1LWF
,
6VQY
,
3DI6
,
1E6J
,
5T82
,
1S1U
,
7XJ5
,
3T19
,
5HRR
,
3KT2
,
4B3Q
,
6DV0
,
2HNZ
,
3LP1
,
1VRU
,
8JYJ
,
6BSJ
,
5DGU
,
1ODY
,
2OPS
,
8ESY
,
8F7M
,
1JLB
,
3KJV
,
6OTZ
,
4KV8
,
1QBS
,
3MEE
,
4I7F
,
1FKP
,
3LAL
,
4NCG
,
6VQE
,
6UJZ
,
6EX9
,
1EX4
,
2RF2
,
1RT6
,
5XOS
,
6SLU
,
1BVE
,
3DOK
,
7R80
,
1ESK
,
1C1B
,
6SKM
,
6WPF
,
4Q1X
,
3QIO
,
1JLE
,
6DJ5
,
6OR7
,
1LW2
,
1NCP
,
2OPP
,
3MEC
,
3T1A
,
1BV9
,
1TKT
,
6UIS
,
5J2M
,
6UJY
,
1HIV
,
3LAN
,
1VRT
,
5IM7
,
6J1W
,
1DTQ
,
1REV
,
6P2G
,
2KOD
,
1RT7
,
1S1T
,
6VQ2
,
1RTJ
,
7SLS
,
1HVH
,
6E9A
,
1C1C
,
6SKN
,
1LWE
,
3DLE
,
8JYH
,
1ODW
,
1LWC
,
6BSI
,
1JLF
,
3DRR
,
8TCL
,
2OPQ
,
1TKZ
,
1JLA
,
6P1I
,
5J2N
,
6UK0
,
3DRP
,
6WPJ
,
2WON
,
1KLM
,
5VZ6
,
3E01
,
3I0R
,
3M8Q
,
1LV1
,
1RT5
,
8FCC
,
3KK1
,
6E7J
,
4QLH
,
1T05
,
7R7V
,
8ERX
,
3MEG
,
8F0F
,
6BSH
,
3C6U
,
1JKH
,
2YNF
,
5HRP
,
7DPQ
,
3QIP
,
1RTH
,
1BWB
,
2YNH
,
1TL1
,
6WPH
,
1C0U
,
1A30
,
6VQD
,
6DJ1
,
5J2Q
,
1JLQ
,
3PHV
,
2WOM
,
3AO2
,
7DOZ
,
8FCE
,
8TCJ
,
3M8P
,
7XJ7
,
5KAO
,
3KT5
,
6J1V
,
5EU7
,
7DT9
,
6P1X
,
3DOL
,
1G6L
,
4Q1Y
,
3DLG
,
3C6T
,
5K14
,
2WHH
,
5HRN
,
1RTI
,
1JLC
,
4U1H
,
2YNG
,
1LW0
,
1TKX
,
3DRS
,
6UJX
,
1QBU
,
1TL3
,
5J2P
,
6UIR
,
6VQZ
,
1S1X
,
1HXB
,
3I0S
,
8FCD
,
1S1V
,
3KK3
,
1RT4
,
1RTD
,
2RKI
,
6WB1
,
4B3P
,
1HVR
,
1BVG
,
5XOT
,
3DOX
,
1FK9
,
3N3I
,
4U7Q
,
8TCM
,
4U1I
,
1RT1
,
1QBT
,
1C0T
,
6DJ2
,
3LAK
,
6SMU
,
8JYI
,
6BJ2
,
1DMP
,
6PYL
,
6DV4
,
6GL1
,
1EXQ
,
3KK2
,
4KSE
,
4B3O
,
5YRS
,
3DYA
,
6WAZ
,
3LP0
,
4Q5M
,
6BSG
,
5TC2
,
2NPH
,
1TAM
,
8ESX
,
1EP4
,
1BWA
,
6DJ7
,
1RT2
,
1BV7
,
2YNI
,
3MED
,
3TAM
,
2HND
,
3DMJ
,
6EWA
,
3FFI
,
6BJ3
,
6UIT
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04585 gag-pol
20
MA (P04585) protein [cytosol]
(R-HIV-3006252)
p6 (P04585) protein [cytosol]
(R-HIV-3072746)
IN (Integrase) (P04585) protein [cytosol]
(R-HIV-173387)
p51 (RT) [cytosol]
(R-HIV-173834)
Reverse transcriptase/ribonuclease H [cytosol]
(R-HIV-173370)
NC (P04585) protein [extracellular region]
(R-HIV-3006248)
MA (P04585) protein [extracellular region]
(R-HIV-175359)
IN (Integrase) (P04585) protein [extracellular region]
(R-HIV-175406)
PR (Protease) (P04585) protein [extracellular region]
(R-HIV-173391)
CA (P04585) protein [extracellular region]
(R-HIV-175492)
Reverse transcriptase/ribonuclease H [extracellular region]
(R-HIV-175316)
p51 (RT) [extracellular region]
(R-HIV-175342)
p6 (P04585) protein [extracellular region]
(R-HIV-175560)
PR (Protease) (P04585) protein [cytosol]
(R-HIV-175182)
CA (P04585) protein [cytosol]
(R-HIV-3006247)
NC (P04585) protein [cytosol]
(R-HIV-3006251)
p6 (P04585) [nucleoplasm]
(R-HIV-175300)
IN (Integrase) (P04585) protein [nucleoplasm]
(R-HIV-175288)
MA (P04585) protein [nucleoplasm]
(R-HIV-3006250)
GAG-POL Polyprotein (P04585) [plasma membrane]
(R-HIV-3076336)
0.73
29
UniProt:P03366 POL
0.623
2
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