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NS2B3 [cytosol]
Stable Identifier
R-DVI-3244638
Type
Complex
Species
Dengue virus type 2
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Dengue Virus Infection (Homo sapiens)
Dengue Virus Genome Translation and Replication (Homo sapiens)
Maturation of DENV proteins (Homo sapiens)
NS2B binds NS3 (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3 binds Dengue protease inhibitors (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3:Dengue protease inhibitor [cytosol] (Dengue virus type 2)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3 cleaves C-prM-E-NS1-NS2A (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3 cleaves NS4AB (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3 cleaves polyprotein (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3:Dengue protease inhibitor [cytosol] (Dengue virus type 2)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3 cleaves prepro-C at the C-prM junction (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3 localizes to nucleus (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
Dengue Virus-Host Interactions (Homo sapiens)
Dengue virus activates/modulates innate and adaptive immune responses (Homo sapiens)
DENV protease NS2B3 binds STING (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3:STING [endoplasmic reticulum membrane] (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
DENV protease NS2B3 cleaves STING (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3:STING [endoplasmic reticulum membrane] (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3 binds IKBKE (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3:IKBKE [cytosol] (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
Dengue virus modulates apoptosis (Homo sapiens)
NS2B3 binds NFKBIA (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3:NFKBIA [cytosol] (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3 binds NFKBIB (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3:NFKBIB [cytosol] (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
NS2B3 cleaves FAM134B (Homo sapiens)
NS2B3 [cytosol] (Dengue virus type 2)
Literature References
PubMed ID
Title
Journal
Year
10744671
Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro
Yusof, R
,
Clum, S
,
Wetzel, M
,
Murthy, HM
,
Padmanabhan, R
J. Biol. Chem.
2000
Participants
components
K27polyUb-NS3 [endoplasmic reticulum membrane]
(Dengue virus type 2)
NS2B [cytosol]
(Dengue virus type 2)
Participates
as a component of
NS2B3:NFKBIB [cytosol] (Homo sapiens)
NS2B3:NFKBIA [cytosol] (Homo sapiens)
NS2B3:IKBKE [cytosol] (Homo sapiens)
NS2B3:STING [endoplasmic reticulum membrane] (Homo sapiens)
NS2B3:Dengue protease inhibitor [cytosol] (Dengue virus type 2)
as an input of
NS2B3 binds NFKBIB (Homo sapiens)
NS2B3 binds NFKBIA (Homo sapiens)
NS2B3 binds IKBKE (Homo sapiens)
DENV protease NS2B3 binds STING (Homo sapiens)
NS2B3 localizes to nucleus (Homo sapiens)
NS2B3 binds Dengue protease inhibitors (Homo sapiens)
as an output of
DENV protease NS2B3 cleaves STING (Homo sapiens)
NS2B binds NS3 (Homo sapiens)
Disease
Name
Identifier
Synonyms
dengue disease
DOID:12205
breakbone fever, Dengue Fever, classic dengue
Cross References
Mondo
0005502
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