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About
What is Reactome ?
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Team
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Release Calendar
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Our Logo
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Digital Preservation
Contact us
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Table of Contents
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phospho-p-Y349,Y350,Y427-SHC1 [cytosol]
Stable Identifier
R-CFA-912321
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
A0A8I3NUU1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
RET signaling (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
SHC1 in the RET complex is phosphorylated (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
p-5Y-RET complexes bind GRB2 (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-2 family signaling (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Phosphorylated SHC recruits GRB2:SOS1 (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Phosphorylated SHC1 recruits GRB2:GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Phosphorylated SHC1 recruits SHIP (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
The SHC1:SHIP1 complex is stabilized by GRB2 (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Phosphorylated SHC recruits GRB2:SOS1 (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Phosphorylated SHC1 recruits GRB2:GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Phosphorylated SHC1 recruits SHIP (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
The SHC1:SHIP1 complex is stabilized by GRB2 (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
RAS GEFs [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (s) signalling events (Canis familiaris)
GPER1 signaling (Canis familiaris)
p-SHC1 binds integrin alpha5beta1:fibronectin (Canis familiaris)
integrin alpha5beta1:Fibronectin matrix:pY-SHC1 [plasma membrane] (Canis familiaris)
pY-SHC1 [cytosol] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
pY-SHC1 [cytosol] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by ERBB2 (Canis familiaris)
SHC1 events in ERBB2 signaling (Canis familiaris)
Activated PKC phosphorylates SHC1 (Canis familiaris)
p-3Y-SHC1-1,p-3Y-SHC1-2 [cytosol] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Canis familiaris)
IGF1R signaling cascade (Canis familiaris)
SHC-related events triggered by IGF1R (Canis familiaris)
GRB2-1:SOS1 binds p-3Y-SHC1 (Canis familiaris)
GRB2-1:SOS1:p-3Y-SHC1 [cytosol] (Canis familiaris)
p-3Y-SHC1 [cytosol] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
p-3Y-SHC1 [cytosol] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
IGF1R phosphorylates SHC1 (Canis familiaris)
IGF1,2:p-3Y-IGF1R:p-3Y-SHC1 [plasma membrane] (Canis familiaris)
p-3Y-SHC1 [cytosol] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
p-3Y-SHC1 dissociates from IGF1R (Canis familiaris)
IGF1,2:p-3Y-IGF1R:p-3Y-SHC1 [plasma membrane] (Canis familiaris)
p-3Y-SHC1 [cytosol] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
p-3Y-SHC1 [cytosol] (Canis familiaris)
phospho-p-Y349,Y350,Y427-SHC1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NUU1
Reference Genes
ENSEMBL:ENSCAFG00845014088.1
UCSC:A0A8I3NUU1
Other Identifiers
490439
Cfa.14843.1.A1_at
Cfa.18402.1.S1_s_at
Cfa.4908.1.A1_s_at
Cfa.5719.1.A1_at
CfaAffx.26236.1.S1_s_at
GO:0001525
GO:0001784
GO:0005068
GO:0005158
GO:0005159
GO:0005168
GO:0005737
GO:0005886
GO:0006355
GO:0007173
GO:0007507
GO:0008286
GO:0030036
GO:0030971
GO:0035556
GO:0042127
GO:0042742
GO:0043066
GO:0043410
GO:0045892
GO:0045893
GO:0046875
GO:0048009
GO:0048408
GO:0048856
GO:0060090
GO:0070374
GO:0071363
GO:0098542
GO:0098609
Participates
as a member of
p-3Y-SHC1 [cytosol] (Canis familiaris)
p-3Y-SHC1-1,p-3Y-SHC1-2 [cytosol] (Canis familiaris)
as a candidate of
pY-SHC1 [cytosol] (Canis familiaris)
as a component of
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Canis familiaris)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
Other forms of this molecule
SHC1-2 [plasma membrane]
SHC1 [plasma membrane]
SHC1-1(156-583) [plasma membrane]
phospho-p-S139,3Y-SHC1-1 [cytosol]
phospho-p-S29,3Y-SHC1-2 [cytosol]
phospho-p-Y194,Y195,Y272-SHC1-3 [cytosol]
SHC1-3 [cytosol]
SHC1-2 [cytosol]
phospho-p-Y317-SHC1-2 [cytosol]
phospho-p-Y239,Y240,Y317-SHC1-2 [cytosol]
phospho-p-Y427-SHC1 [cytosol]
phospho-p-Y349,Y350-SHC1 [cytosol]
phospho-p-Y194,Y195,Y272-SHC1-3 [plasma membrane]
phospho-p-Y239,Y240,Y317-SHC1-2 [plasma membrane]
SHC1 [cytosol]
phospho-p-Y-SHC1 [cytosol]
Inferred From
p-Y349,Y350,Y427-SHC1-1 [cytosol]
(Homo sapiens)
p-Y349,Y350,Y427-SHC1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 427 (in Homo sapiens)
Coordinate
427
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 349 (in Homo sapiens)
Coordinate
349
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 350 (in Homo sapiens)
Coordinate
350
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
ENSEMBL
ENSCAFT00845025220
,
ENSCAFP00845019833
,
ENSCAFG00845014088
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