Reactome | IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane]

IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane]

Stable Identifier

R-CFA-913412

Type

Complex

Species

Canis familiaris

Compartment

plasma membrane

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- MAPK family signaling cascades (Canis familiaris)
  - MAPK1/MAPK3 signaling (Canis familiaris)
    - RAF/MAP kinase cascade (Canis familiaris)
      - RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
        
        RAS GEFs [plasma membrane] (Canis familiaris)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Canis familiaris)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)
        
        IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Canis familiaris)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Participates

as a member of

High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Canis familiaris)

Inferred From

IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)

Cite Us!