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phospho-SHC1 [cytosol]
Stable Identifier
R-CFA-8851895
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
p-Y317-SHC1-2, A0A8I3NUU1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
RAS GEFs [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Canis familiaris)
phospho-SHC1 [cytosol] (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (s) signalling events (Canis familiaris)
GPER1 signaling (Canis familiaris)
p-SHC1 binds integrin alpha5beta1:fibronectin (Canis familiaris)
integrin alpha5beta1:Fibronectin matrix:pY-SHC1 [plasma membrane] (Canis familiaris)
phospho-SHC1 [cytosol] (Canis familiaris)
phospho-SHC1 [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by MET (Canis familiaris)
MET activates RAS signaling (Canis familiaris)
MET phosphorylates SHC1-2 (Canis familiaris)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Canis familiaris)
phospho-SHC1 [cytosol] (Canis familiaris)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Canis familiaris)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Canis familiaris)
phospho-SHC1 [cytosol] (Canis familiaris)
SHC1-2 bound to MET recruits GRB2:SOS1 (Canis familiaris)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Canis familiaris)
phospho-SHC1 [cytosol] (Canis familiaris)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Canis familiaris)
phospho-SHC1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NUU1
Gene Names
SHC1
Reference Genes
ENSEMBL:ENSCAFG00845014088.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845014088.1 SHC1
Other Identifiers
490439
Cfa.14843.1.A1_at
Cfa.18402.1.S1_s_at
Cfa.4908.1.A1_s_at
Cfa.5719.1.A1_at
CfaAffx.26236.1.S1_s_at
GO:0001525
GO:0001784
GO:0005068
GO:0005158
GO:0005159
GO:0005168
GO:0005886
GO:0006351
GO:0006355
GO:0007010
GO:0007155
GO:0007173
GO:0007507
GO:0012501
GO:0023052
GO:0030036
GO:0030971
GO:0035556
GO:0042127
GO:0042742
GO:0043066
GO:0043410
GO:0045892
GO:0045893
GO:0046875
GO:0048009
GO:0048408
GO:0048856
GO:0060090
GO:0070374
GO:0071363
GO:0098542
GO:0098609
Participates
as an input of
p-SHC1 binds integrin alpha5beta1:fibronectin (Canis familiaris)
as a component of
integrin alpha5beta1:Fibronectin matrix:pY-SHC1 [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Canis familiaris)
Other forms of this molecule
SHC1 [plasma membrane]
SHC1 [plasma membrane]
SHC1 [plasma membrane]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
SHC1 [cytosol]
SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [plasma membrane]
phospho-SHC1 [plasma membrane]
phospho-SHC1 [cytosol]
SHC1 [cytosol]
phospho-SHC1 [cytosol]
Inferred From
pY-SHC1 [cytosol]
(Homo sapiens)
p-Y317-SHC1-2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 317 (in Homo sapiens)
Coordinate
317
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
OpenTargets
ENSG00000160691
Ensembl
ENSCAFG00845014088
,
ENSCAFP00845019833
,
ENSCAFT00845025220
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