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AKR1C4 [cytosol]
Stable Identifier
R-CFA-192142
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
F1PZ35
Locations in the PathwayBrowser
Expand all
Drug ADME (Canis familiaris)
Prednisone ADME (Canis familiaris)
AKR1C1 hydrogenates PREDN,PREDL (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Arachidonic acid metabolism (Canis familiaris)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Canis familiaris)
PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
PGH2 is reduced to PGF2a by AKR1C3 (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Synthesis of bile acids and bile salts (Canis familiaris)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Canis familiaris)
5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Canis familiaris)
5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Canis familiaris)
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of fat-soluble vitamins (Canis familiaris)
Retinoid metabolism and transport (Canis familiaris)
AKRs reduce RBP2:atRAL to RBP2:atROL (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
Sensory Perception (Canis familiaris)
Visual phototransduction (Canis familiaris)
Retinoid metabolism and transport (Canis familiaris)
AKRs reduce RBP2:atRAL to RBP2:atROL (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
Signaling by Retinoic Acid (Canis familiaris)
RA biosynthesis pathway (Canis familiaris)
AKR1C3 reduces atRAL to atROL (Canis familiaris)
AKR1C4 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:F1PZ35
Reference Genes
ENSEMBL:ENSCAFG00000005276
Inferred From
AKRs [cytosol]
(Homo sapiens)
Aldo-keto reductase family [cytosol]
(Homo sapiens)
AKR1C4 [cytosol]
(Homo sapiens)
AKR1C1 [cytosol]
(Homo sapiens)
AKR1C2 [cytosol]
(Homo sapiens)
AKR1C3 [cytosol]
(Homo sapiens)
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