Reactome | CASP8 [cytosol]

CASP8 [cytosol]

Stable Identifier

R-BTA-3465404

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

CASP8(1-374), Q2LGB8

Locations in the PathwayBrowser

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Programmed Cell Death (Bos taurus)

- Apoptosis (Bos taurus)
  - Caspase activation via extrinsic apoptotic signalling pathway (Bos taurus)
    - Caspase activation via Death Receptors in the presence of ligand (Bos taurus)
      - Regulation by c-FLIP (Bos taurus)
        
        Caspase-8 and FLIP(L) processing at DISC (Bos taurus)
        
        DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Bos taurus)
        
        CASP8 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:Q2LGB8

Gene Names

CASP8

Reference Genes

BioGPS Gene:507481 CASP8

ENSEMBL:ENSBTAG00000015718.5

KEGG:bta:507481 CASP8

Monarch:507481 CASP8

NCBI Gene:507481 CASP8

UCSC:Q2LGB8 CASP8

Reference Transcript

Other Identifiers

507481

GO:0004197

GO:0005515

GO:0005737

GO:0005829

GO:0006508

GO:0006915

GO:0006954

GO:0008233

GO:0008234

GO:0008625

GO:0030027

GO:0030335

GO:0031264

GO:0031265

GO:0031625

GO:0032731

GO:0032991

GO:0034612

GO:0035877

GO:0036462

GO:0042802

GO:0042981

GO:0043123

GO:0043124

GO:0045651

GO:0045862

GO:0051603

GO:0051604

GO:0060546

GO:0070269

GO:0071260

GO:0097110

GO:0097190

GO:0097191

GO:0097194

GO:0097342

GO:0140639

GO:1900119

Participates

as a component of

Other forms of this molecule

CASP8 [cytosol]

CASP8 [mitochondrial outer membrane]

CASP8 [cytosol]

Inferred From

CASP8(1-374) [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_005202672.1, NP_001039435.1

ENSEMBL

ENSBTAT00000038313, ENSBTAG00000015718, ENSBTAP00000038128

VGNC

26784

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