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CASP9 [cytosol]
Stable Identifier
R-BTA-3465357
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
FLIP(S), E1BNU2
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Bos taurus)
Apoptosis (Bos taurus)
Caspase activation via extrinsic apoptotic signalling pathway (Bos taurus)
Caspase activation via Death Receptors in the presence of ligand (Bos taurus)
Dimerization of procaspase-8 (Bos taurus)
FAS-mediated dimerization of procaspase-8 (Bos taurus)
CASP9 [cytosol] (Bos taurus)
TNF-mediated dimerization of procaspase-8 (Bos taurus)
CASP9 [cytosol] (Bos taurus)
TRAIL-mediated dimerization of procaspase-8 (Bos taurus)
CASP9 [cytosol] (Bos taurus)
Regulated Necrosis (Bos taurus)
RIPK1-mediated regulated necrosis (Bos taurus)
Regulation of necroptotic cell death (Bos taurus)
CASP8 activity is inhibited (Bos taurus)
FLIP(S) and procaspase-8 form heterodimer (Bos taurus)
CASP9 [cytosol] (Bos taurus)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Bos taurus)
CASP9 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BNU2
Gene Names
CASP9
Reference Genes
ENSEMBL:ENSBTAG00000002472.6
ENSEMBL:ENSBTAG00000002472.7 CASP9
Other Identifiers
100140945
GO:0003824
GO:0004197
GO:0005737
GO:0006508
GO:0008233
GO:0008234
GO:0008630
GO:0012501
GO:0016787
GO:0023052
GO:0042981
GO:0043065
GO:0097199
GO:0140096
Participates
as an input of
FLIP(S) and procaspase-8 form heterodimer (Bos taurus)
as a component of
DISC:procaspase-8:FLIP(S) [plasma membrane] (Bos taurus)
This entity regulates
Negatively
FAS-mediated dimerization of procaspase-8
(Bos taurus)
TRAIL-mediated dimerization of procaspase-8
(Bos taurus)
TNF-mediated dimerization of procaspase-8
(Bos taurus)
Other forms of this molecule
CASP9 [cytosol]
CASP9 [cytosol]
phospho-CASP9 [cytosol]
phospho-CASP9 [cytosol]
CASP9 [cytosol]
CASP9 [cytosol]
CASP9 [cytosol]
CASP9 [cytosol]
CASP9 [cytosol]
Inferred From
FLIP(S) [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000132906
Ensembl
ENSBTAP00000003205
,
ENSBTAG00000002472
,
ENSBTAT00000003205
VGNC
106670
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