Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm]
Stable Identifier
R-BTA-174109
Type
Complex
Species
Bos taurus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
Regulation of mitotic cell cycle (Bos taurus)
APC/C-mediated degradation of cell cycle proteins (Bos taurus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Bos taurus)
APC/C:Cdh1 polyubiquitinates SKP2 (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
APC/C:Cdh1-mediated degradation of Skp2 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Bos taurus)
Phosphorylation of the APC/C (Bos taurus)
Free APC/C phosphorylated by Cyclin B:Cdc2 (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Free APC/C phosphorylated by Plk1 (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Autodegradation of Cdh1 by Cdh1:APC/C (Bos taurus)
Degradation of multiubiquitinated Cdh1 (Bos taurus)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Multiubiquitination of APC/C-associated Cdh1 (Bos taurus)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Regulation of APC/C activators between G1/S and early anaphase (Bos taurus)
Association of Cyclin A:Cdk2 with Cdh1 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Dissociation of phospho-Cdh1 from the APC/C complex (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
Senescence-Associated Secretory Phenotype (SASP) (Bos taurus)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Cdh1:APC/C complex binds EHMT1:EHMT2 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Bos taurus)
EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
DNA Replication (Bos taurus)
DNA Replication Pre-Initiation (Bos taurus)
Assembly of the pre-replicative complex (Bos taurus)
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ANAPC1 [nucleoplasm]
(Bos taurus)
ANAPC10 [nucleoplasm]
(Bos taurus)
ANAPC15 [nucleoplasm]
(Bos taurus)
ANAPC16 [nucleoplasm]
(Bos taurus)
ANAPC2 [nucleoplasm]
(Bos taurus)
ANAPC4 [nucleoplasm]
(Bos taurus)
ANAPC5 [nucleoplasm]
(Bos taurus)
ANAPC7 [nucleoplasm]
(Bos taurus)
CDC16 [nucleoplasm]
(Bos taurus)
CDC23 [nucleoplasm]
(Bos taurus)
CDC26 [nucleoplasm]
(Bos taurus)
CDC27 [nucleoplasm]
(Bos taurus)
Homologues of ANAPC11 [nucleoplasm]
(Bos taurus)
UBE2C [nucleoplasm]
(Bos taurus)
UBE2D1 [nucleoplasm]
(Bos taurus)
UBE2E1 [nucleoplasm]
(Bos taurus)
UBE2S [nucleoplasm]
(Bos taurus)
Participates
as an output of
Free APC/C phosphorylated by Cyclin B:Cdc2 (Bos taurus)
Free APC/C phosphorylated by Plk1 (Bos taurus)
Dissociation of phospho-Cdh1 from the APC/C complex (Bos taurus)
Degradation of multiubiquitinated Cdh1 (Bos taurus)
as an input of
Free APC/C phosphorylated by Cyclin B:Cdc2 (Bos taurus)
Free APC/C phosphorylated by Plk1 (Bos taurus)
as a component of
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
Inferred From
anaphase promoting complex (APC/C) [nucleoplasm]
(Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm]
(Homo sapiens)
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
