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UBE2C [nucleoplasm]
Stable Identifier
R-BTA-174188
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
UBE2C, Q32PA5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
Regulation of mitotic cell cycle (Bos taurus)
APC/C-mediated degradation of cell cycle proteins (Bos taurus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Bos taurus)
APC/C:Cdh1 polyubiquitinates SKP2 (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
APC/C:Cdh1-mediated degradation of Skp2 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Bos taurus)
Phosphorylation of the APC/C (Bos taurus)
Free APC/C phosphorylated by Cyclin B:Cdc2 (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Free APC/C phosphorylated by Plk1 (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Autodegradation of Cdh1 by Cdh1:APC/C (Bos taurus)
Degradation of multiubiquitinated Cdh1 (Bos taurus)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Multiubiquitination of APC/C-associated Cdh1 (Bos taurus)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Regulation of APC/C activators between G1/S and early anaphase (Bos taurus)
Association of Cyclin A:Cdk2 with Cdh1 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Dissociation of phospho-Cdh1 from the APC/C complex (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
Senescence-Associated Secretory Phenotype (SASP) (Bos taurus)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Cdh1:APC/C complex binds EHMT1:EHMT2 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Bos taurus)
EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
DNA Replication (Bos taurus)
DNA Replication Pre-Initiation (Bos taurus)
Assembly of the pre-replicative complex (Bos taurus)
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Protein ubiquitination (Bos taurus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Bos taurus)
UBA1 conjugates ubiquitin to nuclear E2 enzymes (Bos taurus)
E2 ubiquitin conjugating enzyme (UBA1 substrate) [nucleoplasm] (Bos taurus)
UBE2C [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:Q32PA5
Gene Names
UBE2C
Reference Genes
BioGPS Gene:506962 UBE2C
ENSEMBL:ENSBTAG00000016746
KEGG Gene (Bos taurus):506962 UBE2C
Monarch:506962 UBE2C
NCBI Gene:506962 UBE2C
Reference Transcript
RefSeq:NM_001037449.2 UBE2C
Other Identifiers
506962
GO:0000151
GO:0000166
GO:0000209
GO:0000278
GO:0003824
GO:0004842
GO:0005524
GO:0005634
GO:0005680
GO:0005829
GO:0005886
GO:0006511
GO:0007049
GO:0007059
GO:0010458
GO:0010994
GO:0016567
GO:0016740
GO:0019538
GO:0030071
GO:0030163
GO:0031145
GO:0031536
GO:0036211
GO:0043226
GO:0044389
GO:0045842
GO:0051301
GO:0061631
GO:0065003
GO:0070936
GO:0070979
GO:0140014
GO:0140096
Participates
as a member of
E2 ubiquitin conjugating enzyme (UBA1 substrate) [nucleoplasm] (Bos taurus)
as a component of
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Other forms of this molecule
UBE2C [cytosol]
UBE2C [nucleoplasm]
UBE2C [cytosol]
Inferred From
UBE2C [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001032526.1
OpenTargets
ENSG00000175063
Ensembl
ENSBTAT00000079595
,
ENSBTAP00000061332
,
ENSBTAG00000016746
VGNC
36578
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