Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
UBE2S [nucleoplasm]
Stable Identifier
R-BTA-8852051
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
UBE2S, Q1RML1
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
Regulation of mitotic cell cycle (Bos taurus)
APC/C-mediated degradation of cell cycle proteins (Bos taurus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Bos taurus)
APC/C:Cdh1 polyubiquitinates SKP2 (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
APC/C:Cdh1-mediated degradation of Skp2 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Bos taurus)
Phosphorylation of the APC/C (Bos taurus)
Free APC/C phosphorylated by Cyclin B:Cdc2 (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Free APC/C phosphorylated by Plk1 (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Autodegradation of Cdh1 by Cdh1:APC/C (Bos taurus)
Degradation of multiubiquitinated Cdh1 (Bos taurus)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Multiubiquitination of APC/C-associated Cdh1 (Bos taurus)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Regulation of APC/C activators between G1/S and early anaphase (Bos taurus)
Association of Cyclin A:Cdk2 with Cdh1 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Dissociation of phospho-Cdh1 from the APC/C complex (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
Senescence-Associated Secretory Phenotype (SASP) (Bos taurus)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Bos taurus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Cdh1:APC/C complex binds EHMT1:EHMT2 (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Bos taurus)
EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] (Bos taurus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
DNA Replication (Bos taurus)
DNA Replication Pre-Initiation (Bos taurus)
Assembly of the pre-replicative complex (Bos taurus)
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Bos taurus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Protein ubiquitination (Bos taurus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Bos taurus)
UBA1 conjugates ubiquitin to nuclear E2 enzymes (Bos taurus)
E2 ubiquitin conjugating enzyme (UBA1 substrate) [nucleoplasm] (Bos taurus)
UBE2S [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:Q1RML1
Gene Names
UBE2S
Reference Genes
BioGPS Gene:617703 UBE2S
ENSEMBL:ENSBTAG00000009211
ENSEMBL:ENSBTAG00000009211.5 UBE2S
KEGG Gene (Bos taurus):617703 UBE2S
Monarch:617703 UBE2S
NCBI Gene:617703 UBE2S
Reference Transcript
RefSeq:NM_001076472.2 UBE2S
Other Identifiers
617703
Participates
as a member of
E2 ubiquitin conjugating enzyme (UBA1 substrate) [nucleoplasm] (Bos taurus)
as a component of
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Bos taurus)
Other forms of this molecule
UBE2S [cytosol]
UBE2S [nucleoplasm]
UBE2S [cytosol]
Inferred From
UBE2S [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001069940.1
OpenTargets
ENSG00000108106
IntEnz
2.3.2.23
Ensembl
ENSBTAG00000009211
,
ENSBTAT00000012136
,
ENSBTAP00000012136
VGNC
36595
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text