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urate [extracellular region]
Stable Identifier
R-ALL-429056
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
Uric acid, 7,9-dihydro-1H-purine-2,6,8(3H)-trione
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Sus scrofa
Xenopus tropicalis
Expand all
Transport of small molecules (Bos taurus)
Ion channel transport (Bos taurus)
Stimuli-sensing channels (Bos taurus)
SLC17A3-2 transports cytosolic urate to extracellular region (Bos taurus)
urate [extracellular region]
SLC-mediated transmembrane transport (Bos taurus)
Cellular hexose transport (Bos taurus)
SLC2A9 transports Fru, Glc, urate (Bos taurus)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Organic cation/anion/zwitterion transport (Bos taurus)
Organic anion transport (Bos taurus)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Bos taurus)
urate [extracellular region]
Transport of small molecules (Caenorhabditis elegans)
Ion channel transport (Caenorhabditis elegans)
Stimuli-sensing channels (Caenorhabditis elegans)
SLC17A3-2 transports cytosolic urate to extracellular region (Caenorhabditis elegans)
urate [extracellular region]
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Cellular hexose transport (Caenorhabditis elegans)
SLC2A9 transports Fru, Glc, urate (Caenorhabditis elegans)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Organic cation/anion/zwitterion transport (Caenorhabditis elegans)
Organic anion transport (Caenorhabditis elegans)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Caenorhabditis elegans)
urate [extracellular region]
Transport of small molecules (Canis familiaris)
Ion channel transport (Canis familiaris)
Stimuli-sensing channels (Canis familiaris)
SLC17A3-2 transports cytosolic urate to extracellular region (Canis familiaris)
urate [extracellular region]
SLC-mediated transmembrane transport (Canis familiaris)
Cellular hexose transport (Canis familiaris)
SLC2A9 transports Fru, Glc, urate (Canis familiaris)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Organic cation/anion/zwitterion transport (Canis familiaris)
Organic anion transport (Canis familiaris)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Canis familiaris)
urate [extracellular region]
Transport of small molecules (Dictyostelium discoideum)
Ion channel transport (Dictyostelium discoideum)
Stimuli-sensing channels (Dictyostelium discoideum)
SLC17A3-2 transports cytosolic urate to extracellular region (Dictyostelium discoideum)
urate [extracellular region]
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Cellular hexose transport (Dictyostelium discoideum)
SLC2A9 transports Fru, Glc, urate (Dictyostelium discoideum)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of small molecules (Drosophila melanogaster)
Ion channel transport (Drosophila melanogaster)
Stimuli-sensing channels (Drosophila melanogaster)
SLC17A3-2 transports cytosolic urate to extracellular region (Drosophila melanogaster)
urate [extracellular region]
SLC-mediated transmembrane transport (Drosophila melanogaster)
Cellular hexose transport (Drosophila melanogaster)
SLC2A9 transports Fru, Glc, urate (Drosophila melanogaster)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Organic cation/anion/zwitterion transport (Drosophila melanogaster)
Organic anion transport (Drosophila melanogaster)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Drosophila melanogaster)
urate [extracellular region]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Cellular hexose transport (Gallus gallus)
SLC2A9 transports Fru, Glc, urate (Gallus gallus)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLC22A12 causes renal hypouricemia 1 (RHUC1) (Homo sapiens)
Defective SLC22A12 does not exchange extracellular urate for cytosolic LACT (Homo sapiens)
urate [extracellular region]
Defective SLC2A9 causes hypouricemia renal 2 (RHUC2) (Homo sapiens)
Defective SLC2A9 does not transport Fru, Glc, urate (Homo sapiens)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
SLC17A3-2 transports cytosolic urate to extracellular region (Homo sapiens)
urate [extracellular region]
SLC-mediated transmembrane transport (Homo sapiens)
Cellular hexose transport (Homo sapiens)
SLC2A9 transports Fru, Glc, urate (Homo sapiens)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic anion transport (Homo sapiens)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Homo sapiens)
urate [extracellular region]
Transport of small molecules (Mus musculus)
Ion channel transport (Mus musculus)
Stimuli-sensing channels (Mus musculus)
SLC17A3-2 transports cytosolic urate to extracellular region (Mus musculus)
urate [extracellular region]
SLC-mediated transmembrane transport (Mus musculus)
Cellular hexose transport (Mus musculus)
SLC2A9 transports Fru, Glc, urate (Mus musculus)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Organic cation/anion/zwitterion transport (Mus musculus)
Organic anion transport (Mus musculus)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Mus musculus)
urate [extracellular region]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Cellular hexose transport (Plasmodium falciparum)
SLC2A9 transports Fru, Glc, urate (Plasmodium falciparum)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of small molecules (Rattus norvegicus)
Ion channel transport (Rattus norvegicus)
Stimuli-sensing channels (Rattus norvegicus)
SLC17A3-2 transports cytosolic urate to extracellular region (Rattus norvegicus)
urate [extracellular region]
SLC-mediated transmembrane transport (Rattus norvegicus)
Cellular hexose transport (Rattus norvegicus)
SLC2A9 transports Fru, Glc, urate (Rattus norvegicus)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Organic cation/anion/zwitterion transport (Rattus norvegicus)
Organic anion transport (Rattus norvegicus)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Rattus norvegicus)
urate [extracellular region]
Transport of small molecules (Saccharomyces cerevisiae)
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Cellular hexose transport (Saccharomyces cerevisiae)
SLC2A9 transports Fru, Glc, urate (Saccharomyces cerevisiae)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of small molecules (Sus scrofa)
Ion channel transport (Sus scrofa)
Stimuli-sensing channels (Sus scrofa)
SLC17A3-2 transports cytosolic urate to extracellular region (Sus scrofa)
urate [extracellular region]
SLC-mediated transmembrane transport (Sus scrofa)
Cellular hexose transport (Sus scrofa)
SLC2A9 transports Fru, Glc, urate (Sus scrofa)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Organic cation/anion/zwitterion transport (Sus scrofa)
Organic anion transport (Sus scrofa)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Sus scrofa)
urate [extracellular region]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Cellular hexose transport (Xenopus tropicalis)
SLC2A9 transports Fru, Glc, urate (Xenopus tropicalis)
Fru,Glc,urate [extracellular region]
urate [extracellular region]
External Reference Information
External Reference
7,9-dihydro-1H-purine-2,6,8(3H)-trione [ChEBI:17775]
Participates
as an input of
Defective SLC22A12 does not exchange extracellular urate for cytosolic LACT (Homo sapiens)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Caenorhabditis elegans)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Drosophila melanogaster)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Sus scrofa)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Bos taurus)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Canis familiaris)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Rattus norvegicus)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Mus musculus)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Homo sapiens)
as an output of
SLC17A3-2 transports cytosolic urate to extracellular region (Dictyostelium discoideum)
SLC17A3-2 transports cytosolic urate to extracellular region (Caenorhabditis elegans)
SLC17A3-2 transports cytosolic urate to extracellular region (Drosophila melanogaster)
SLC17A3-2 transports cytosolic urate to extracellular region (Sus scrofa)
SLC17A3-2 transports cytosolic urate to extracellular region (Bos taurus)
SLC17A3-2 transports cytosolic urate to extracellular region (Canis familiaris)
SLC17A3-2 transports cytosolic urate to extracellular region (Rattus norvegicus)
SLC17A3-2 transports cytosolic urate to extracellular region (Mus musculus)
SLC17A3-2 transports cytosolic urate to extracellular region (Homo sapiens)
as a member of
Fru,Glc,urate [extracellular region]
Other forms of this molecule
urate [cytosol]
Cross References
COMPOUND
C00366
PubChem Substance
8144012
HMDB Metabolite
HMDB0000289
ZINC
000002041003
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