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3HKYN [cytosol]
Stable Identifier
R-ALL-34351
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
3-hydroxy-L-kynurenine
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Tryptophan catabolism (Bos taurus)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Bos taurus)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Bos taurus)
3HKYN [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Tryptophan catabolism (Caenorhabditis elegans)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Caenorhabditis elegans)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Caenorhabditis elegans)
3HKYN [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Tryptophan catabolism (Canis familiaris)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Canis familiaris)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Canis familiaris)
3HKYN [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Tryptophan catabolism (Danio rerio)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Danio rerio)
3HKYN [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Tryptophan catabolism (Dictyostelium discoideum)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Dictyostelium discoideum)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Dictyostelium discoideum)
3HKYN [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Tryptophan catabolism (Drosophila melanogaster)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Drosophila melanogaster)
3HKYN [cytosol]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Tryptophan catabolism (Gallus gallus)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Gallus gallus)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Gallus gallus)
3HKYN [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Tryptophan catabolism (Homo sapiens)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Homo sapiens)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Homo sapiens)
3HKYN [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Tryptophan catabolism (Mus musculus)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Mus musculus)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Mus musculus)
3HKYN [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Tryptophan catabolism (Rattus norvegicus)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Rattus norvegicus)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Rattus norvegicus)
3HKYN [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Tryptophan catabolism (Saccharomyces cerevisiae)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Saccharomyces cerevisiae)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Saccharomyces cerevisiae)
3HKYN [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Tryptophan catabolism (Sus scrofa)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Sus scrofa)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Sus scrofa)
3HKYN [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Tryptophan catabolism (Xenopus tropicalis)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Xenopus tropicalis)
3HKYN [cytosol]
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Xenopus tropicalis)
3HKYN [cytosol]
External Reference Information
External Reference
3-hydroxy-L-kynurenine [ChEBI:17380]
Participates
as an input of
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Saccharomyces cerevisiae)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Dictyostelium discoideum)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Caenorhabditis elegans)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Xenopus tropicalis)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Sus scrofa)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Bos taurus)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Canis familiaris)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Rattus norvegicus)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Mus musculus)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Homo sapiens)
3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Gallus gallus)
as an output of
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Saccharomyces cerevisiae)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Dictyostelium discoideum)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Caenorhabditis elegans)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Drosophila melanogaster)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Xenopus tropicalis)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Danio rerio)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Sus scrofa)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Bos taurus)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Canis familiaris)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Rattus norvegicus)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Mus musculus)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Homo sapiens)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Gallus gallus)
Cross References
COMPOUND
C03227
PubChem Substance
8144615
HMDB Metabolite
HMDB0011631
ZINC
000003869266
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