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T3 [cytosol]
Stable Identifier
R-ALL-176667
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
3,5,3'-triiodothyronine, 3,3',5'-triiodothyronine
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase II - Conjugation of compounds (Bos taurus)
Cytosolic sulfonation of small molecules (Bos taurus)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Bos taurus)
T3 [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Metabolism of amine-derived hormones (Bos taurus)
Thyroxine biosynthesis (Bos taurus)
Regulation of thyroid hormone activity (Bos taurus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Bos taurus)
T3 [cytosol]
Thyroxine is deiodinated to triiodothyronine (Bos taurus)
T3 [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of organic anions (Bos taurus)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Bos taurus)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Bos taurus)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Cytosolic sulfonation of small molecules (Caenorhabditis elegans)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Caenorhabditis elegans)
T3 [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of vitamins, nucleosides, and related molecules (Caenorhabditis elegans)
Transport of organic anions (Caenorhabditis elegans)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Caenorhabditis elegans)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Caenorhabditis elegans)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase II - Conjugation of compounds (Canis familiaris)
Cytosolic sulfonation of small molecules (Canis familiaris)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Canis familiaris)
T3 [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Metabolism of amine-derived hormones (Canis familiaris)
Thyroxine biosynthesis (Canis familiaris)
Regulation of thyroid hormone activity (Canis familiaris)
Thyroxine is deiodinated to triiodothyronine (Canis familiaris)
T3 [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of organic anions (Canis familiaris)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Canis familiaris)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Canis familiaris)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase II - Conjugation of compounds (Danio rerio)
Cytosolic sulfonation of small molecules (Danio rerio)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Danio rerio)
T3 [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of vitamins, nucleosides, and related molecules (Danio rerio)
Transport of organic anions (Danio rerio)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Danio rerio)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Danio rerio)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Metabolism of amine-derived hormones (Dictyostelium discoideum)
Thyroxine biosynthesis (Dictyostelium discoideum)
Regulation of thyroid hormone activity (Dictyostelium discoideum)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Dictyostelium discoideum)
T3 [cytosol]
Thyroxine is deiodinated to triiodothyronine (Dictyostelium discoideum)
T3 [cytosol]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of vitamins, nucleosides, and related molecules (Dictyostelium discoideum)
Transport of organic anions (Dictyostelium discoideum)
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Dictyostelium discoideum)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase II - Conjugation of compounds (Drosophila melanogaster)
Cytosolic sulfonation of small molecules (Drosophila melanogaster)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Drosophila melanogaster)
T3 [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of organic anions (Drosophila melanogaster)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Drosophila melanogaster)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Drosophila melanogaster)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase II - Conjugation of compounds (Gallus gallus)
Cytosolic sulfonation of small molecules (Gallus gallus)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Gallus gallus)
T3 [cytosol]
Metabolism of amino acids and derivatives (Gallus gallus)
Metabolism of amine-derived hormones (Gallus gallus)
Thyroxine biosynthesis (Gallus gallus)
Regulation of thyroid hormone activity (Gallus gallus)
Thyroxine is deiodinated to triiodothyronine (Gallus gallus)
T3 [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
Transport of organic anions (Gallus gallus)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Gallus gallus)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Gallus gallus)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Cytosolic sulfonation of small molecules (Homo sapiens)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Homo sapiens)
T3 [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of amine-derived hormones (Homo sapiens)
Thyroxine biosynthesis (Homo sapiens)
Regulation of thyroid hormone activity (Homo sapiens)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Homo sapiens)
T3 [cytosol]
Thyroxine is deiodinated to triiodothyronine (Homo sapiens)
T3 [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of organic anions (Homo sapiens)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Homo sapiens)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Homo sapiens)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase II - Conjugation of compounds (Mus musculus)
Cytosolic sulfonation of small molecules (Mus musculus)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Mus musculus)
T3 [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Metabolism of amine-derived hormones (Mus musculus)
Thyroxine biosynthesis (Mus musculus)
Regulation of thyroid hormone activity (Mus musculus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Mus musculus)
T3 [cytosol]
Thyroxine is deiodinated to triiodothyronine (Mus musculus)
T3 [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of organic anions (Mus musculus)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Mus musculus)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Mus musculus)
T3,T4 [cytosol]
T3 [cytosol]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of vitamins, nucleosides, and related molecules (Plasmodium falciparum)
Transport of organic anions (Plasmodium falciparum)
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Plasmodium falciparum)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase II - Conjugation of compounds (Rattus norvegicus)
Cytosolic sulfonation of small molecules (Rattus norvegicus)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Rattus norvegicus)
T3 [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Metabolism of amine-derived hormones (Rattus norvegicus)
Thyroxine biosynthesis (Rattus norvegicus)
Regulation of thyroid hormone activity (Rattus norvegicus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Rattus norvegicus)
T3 [cytosol]
Thyroxine is deiodinated to triiodothyronine (Rattus norvegicus)
T3 [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of organic anions (Rattus norvegicus)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Rattus norvegicus)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Rattus norvegicus)
T3,T4 [cytosol]
T3 [cytosol]
Transport of small molecules (Saccharomyces cerevisiae)
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Transport of vitamins, nucleosides, and related molecules (Saccharomyces cerevisiae)
Transport of organic anions (Saccharomyces cerevisiae)
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Saccharomyces cerevisiae)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase II - Conjugation of compounds (Sus scrofa)
Cytosolic sulfonation of small molecules (Sus scrofa)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Sus scrofa)
T3 [cytosol]
Metabolism of amino acids and derivatives (Sus scrofa)
Metabolism of amine-derived hormones (Sus scrofa)
Thyroxine biosynthesis (Sus scrofa)
Regulation of thyroid hormone activity (Sus scrofa)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Sus scrofa)
T3 [cytosol]
Thyroxine is deiodinated to triiodothyronine (Sus scrofa)
T3 [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of organic anions (Sus scrofa)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Sus scrofa)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Sus scrofa)
T3,T4 [cytosol]
T3 [cytosol]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase II - Conjugation of compounds (Xenopus tropicalis)
Cytosolic sulfonation of small molecules (Xenopus tropicalis)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Xenopus tropicalis)
T3 [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of vitamins, nucleosides, and related molecules (Xenopus tropicalis)
Transport of organic anions (Xenopus tropicalis)
SLCO1B1 transports T3,T4 from extracellular region to cytosol (Xenopus tropicalis)
T3,T4 [cytosol]
T3 [cytosol]
SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Xenopus tropicalis)
T3,T4 [cytosol]
T3 [cytosol]
External Reference Information
External Reference
3,3',5'-triiodothyronine [ChEBI:28774]
Participates
as an input of
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Caenorhabditis elegans)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Drosophila melanogaster)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Gallus gallus)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Xenopus tropicalis)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Danio rerio)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Sus scrofa)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Bos taurus)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Canis familiaris)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Rattus norvegicus)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Mus musculus)
3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Homo sapiens)
as a member of
T3,T4 [cytosol]
as an output of
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Dictyostelium discoideum)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Sus scrofa)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Bos taurus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Rattus norvegicus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Homo sapiens)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Mus musculus)
Thyroxine is deiodinated to triiodothyronine (Dictyostelium discoideum)
Thyroxine is deiodinated to triiodothyronine (Gallus gallus)
Thyroxine is deiodinated to triiodothyronine (Sus scrofa)
Thyroxine is deiodinated to triiodothyronine (Bos taurus)
Thyroxine is deiodinated to triiodothyronine (Canis familiaris)
Thyroxine is deiodinated to triiodothyronine (Rattus norvegicus)
Thyroxine is deiodinated to triiodothyronine (Homo sapiens)
Thyroxine is deiodinated to triiodothyronine (Mus musculus)
Other forms of this molecule
T3 [extracellular region]
Cross References
Guide to Pharmacology - Ligands
2636
COMPOUND
C07639
PubChem Substance
8144291
HMDB Metabolite
HMDB0060074
ZINC
000004097418
,
000004097417
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