Reactome | L-KYN [cytosol]

L-KYN [cytosol]

Stable Identifier

R-ALL-29970

Type

Chemical Compound [SimpleEntity]

Compartment

cytosol

Synonyms

3-Anthraniloyl-L-alanine, L-kynurenine

Locations in the PathwayBrowser

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External Reference Information

External Reference

L-kynurenine [ChEBI:16946]

Participates

as an input of

kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] (Homo sapiens)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Saccharomyces cerevisiae)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Dictyostelium discoideum)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Caenorhabditis elegans)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Drosophila melanogaster)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Xenopus tropicalis)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Danio rerio)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Sus scrofa)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Bos taurus)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Canis familiaris)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Rattus norvegicus)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Mus musculus)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Homo sapiens)
kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Gallus gallus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Saccharomyces cerevisiae)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Schizosaccharomyces pombe)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Dictyostelium discoideum)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Caenorhabditis elegans)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Drosophila melanogaster)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Xenopus tropicalis)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Danio rerio)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Sus scrofa)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Bos taurus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Canis familiaris)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Rattus norvegicus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Mus musculus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Homo sapiens)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Gallus gallus)

as an output of

N-formylkynurenine + H2O => kynurenine + formate [mouse] (Mus musculus)
AFMID hydrolyses NFK to L-KYN (Homo sapiens)

Other forms of this molecule

L-KYN [mitochondrial matrix]

Cross References

COMPOUND

C00328

PubChem Substance

8144752

HMDB Metabolite

HMDB0000684

ZINC

000000895186

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