Reactome | STAT3 nuclear events downstream of ALK signaling

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10731396
displayName	STAT3 nuclear events downstream of ALK signaling
eventOf	[Pathway:R-XTR-201556] Signaling by ALK - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-9701531] p-Y705,S727 STAT3 is acetylated - Xenopus tropicalis [Reaction:R-XTR-9701565] HDACs deacetylate p-STAT3 dimers - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-9701898] STAT3 nuclear events downstream of ALK signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	STAT3 nuclear events downstream of ALK signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9701898
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-201556] Signaling by ALK
(inferredTo)	[Pathway:R-HSA-9701898] STAT3 nuclear events downstream of ALK signaling

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