Reactome | TST transfers sulfur from S2O3(2-) to HCN to form HSCN

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TST transfers sulfur from S2O3(2-) to HCN to form HSCN Show undefined attributes

catalystActivity	[CatalystActivity:10719804] thiosulfate-cyanide sulfurtransferase activity of TST [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10719806
displayName	TST transfers sulfur from S2O3(2-) to HCN to form HSCN
eventOf	[Pathway:R-XTR-1614558] Degradation of cysteine and homocysteine - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Homo sapiens
input	[SimpleEntity:R-ALL-9013199] HCN [mitochondrial matrix] [SimpleEntity:R-ALL-1614595] S2O3(2-) [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	TST transfers sulfur from S2O3(2-) to HCN to form HSCN hydrogen cyanide + thiosulfate => 2 H(+) + sulfite + thiocyanate
output	2 × [SimpleEntity:R-ALL-193465] H+ [peroxisomal matrix] [SimpleEntity:R-ALL-9013191] HSCN [mitochondrial matrix] [SimpleEntity:R-ALL-9013207] SO3(2-) [mitochondrial matrix]
precedingEvent	[Reaction:R-XTR-9012721] MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9013198
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-1614558] Degradation of cysteine and homocysteine
(inferredTo)	[Reaction:R-HSA-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN

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