Reactome | TST transfers sulfur from S2O3(2-) to HCN to form HSCN

Schema > Reaction > Entries

TST transfers sulfur from S2O3(2-) to HCN to form HSCN Show undefined attributes

authored	[InstanceEdit:9013200] Jassal, Bijay, 2017-07-24
catalystActivity	[CatalystActivity:1614667] thiosulfate-cyanide sulfurtransferase activity of TST [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9013200] Jassal, Bijay, 2017-07-24
crossReference	[DatabaseIdentifier:12668125] RHEA:16881 [DatabaseIdentifier:9930122] RHEA:16882
dbId	9013198
displayName	TST transfers sulfur from S2O3(2-) to HCN to form HSCN
edited	[InstanceEdit:9013200] Jassal, Bijay, 2017-07-24
eventOf	[Pathway:R-HSA-1614558] Degradation of cysteine and homocysteine - Homo sapiens
input	[SimpleEntity:R-ALL-9013199] HCN [mitochondrial matrix] [SimpleEntity:R-ALL-1614595] S2O3(2-) [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9013202] Enzymatic conversion of cyanide to thiocyanate [LiteratureReference:9013196] Cloning and expression of human liver rhodanese cDNA [LiteratureReference:9013205] A partial exploration of the potential energy surfaces of SCN and HSCN: implications for the enzyme-mediated detoxification of cyanide
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	TST transfers sulfur from S2O3(2-) to HCN to form HSCN hydrogen cyanide + thiosulfate => 2 H(+) + sulfite + thiocyanate
orthologousEvent	[Reaction:R-GGA-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Gallus gallus [Reaction:R-PFA-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Plasmodium falciparum [Reaction:R-SCE-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Saccharomyces cerevisiae [Reaction:R-SPO-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Schizosaccharomyces pombe [Reaction:R-DDI-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Dictyostelium discoideum [Reaction:R-CEL-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Caenorhabditis elegans [Reaction:R-XTR-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Xenopus tropicalis [Reaction:R-DRE-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Danio rerio [Reaction:R-SSC-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Sus scrofa [Reaction:R-BTA-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Bos taurus [Reaction:R-CFA-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Canis familiaris [Reaction:R-RNO-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Rattus norvegicus [Reaction:R-MMU-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Mus musculus
output	2 × [SimpleEntity:R-ALL-193465] H+ [peroxisomal matrix] [SimpleEntity:R-ALL-9013191] HSCN [mitochondrial matrix] [SimpleEntity:R-ALL-9013207] SO3(2-) [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-9012721] MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR - Homo sapiens [Reaction:R-HSA-1614618] Persulfide sulfur is transferred onto sulfite - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9034674] Brenner, Matthew, Boss, Gerry, 2018-01-10 [InstanceEdit:9939375] Hill, David P, 2025-02-25
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9013198
summation	[Summation:9013204] Cyanide is a potent metabolic poison, a major component of w...
updateTrackers	[UpdateTracker:9939738] Update Tracker - [Reaction:9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - v92:[removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9939738] Update Tracker - [Reaction:9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - v92:[removeOutput]
(hasEvent)	[Pathway:R-HSA-1614558] Degradation of cysteine and homocysteine