Reactome | Degradation of cysteine and homocysteine

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Degradation of cysteine and homocysteine Show undefined attributes

created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10558856
displayName	Degradation of cysteine and homocysteine
eventOf	[Pathway:R-XTR-1614635] Sulfur amino acid metabolism - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:10172] sulfur amino acid catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-1614631] Homocysteine is degraded to oxobutanoate and H2S - Xenopus tropicalis [Reaction:R-XTR-1614614] Cysteine is degraded to serine and H2S - Xenopus tropicalis [Reaction:R-XTR-1614645] CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine - Xenopus tropicalis [Reaction:R-XTR-6814153] ADO oxidises 2AET to HTAU - Xenopus tropicalis [Reaction:R-XTR-6814165] PXLP-K333-GADL1 decarboxylates CSA to HTAU - Xenopus tropicalis [Reaction:R-XTR-1655453] FMO1:FAD oxidizes HTAU to TAU - Xenopus tropicalis [Reaction:R-XTR-1614567] Excess homocysteine yields homolanthionine and H2S - Xenopus tropicalis [Reaction:R-XTR-1614591] Excess cysteine yields lanthionine and H2S - Xenopus tropicalis [Reaction:R-XTR-9034756] MPST transfers sulfur atom from 3MPYR to form CysS248-MPST - Xenopus tropicalis [Reaction:R-XTR-9035227] TXN2 binds CysS248-MPST - Xenopus tropicalis [Reaction:R-XTR-9035484] CysS248-MPST:TXN2 dissociates - Xenopus tropicalis [Reaction:R-XTR-9012721] MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR - Xenopus tropicalis [Reaction:R-XTR-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Xenopus tropicalis [Reaction:R-XTR-9013533] MPST transfers sulfur from sulfanegen to HCN to form HSCN - Xenopus tropicalis [Reaction:R-XTR-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Xenopus tropicalis [Pathway:R-XTR-1614517] Sulfide oxidation to sulfate - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-1614558] Degradation of cysteine and homocysteine - Homo sapiens
isInDisease	false
isInferred	true
name	Degradation of cysteine and homocysteine
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-1614558
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-1614635] Sulfur amino acid metabolism
(inferredTo)	[Pathway:R-HSA-1614558] Degradation of cysteine and homocysteine

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