Reactome | SOCS-1 and SOCS-3 [cytosol]

Schema > DefinedSet > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-XTR-9705731] SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] - Xenopus tropicalis [Complex:R-XTR-9705731] SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] - Xenopus tropicalis [Complex:R-XTR-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10679912
displayName	SOCS-1 and SOCS-3 [cytosol]
hasMember	[EntityWithAccessionedSequence:R-XTR-204910] socs1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-XTR-873794] socs3 [cytosol] - Xenopus tropicalis
inDisease	false
inferredFrom	[DefinedSet:R-HSA-877267] SOCS-1 and SOCS-3 [cytosol] - Homo sapiens
maxDepth	2
name	SOCS-1 and SOCS-3
producedByEvent	[BlackBoxEvent:R-XTR-9705738] SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 - Xenopus tropicalis [BlackBoxEvent:R-XTR-9705738] SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 - Xenopus tropicalis
schemaClass	DefinedSet
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-877267

(output)	[BlackBoxEvent:R-XTR-9705738] SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7
(hasComponent)	[Complex:R-XTR-9705731] SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] [Complex:R-XTR-976147] RBX1-CUL5-EloB/C-SOCS [cytosol]
(inferredTo)	[DefinedSet:R-HSA-877267] SOCS-1 and SOCS-3 [cytosol]