Reactome | G2/M Checkpoints

Schema > Pathway > Entries

G2/M Checkpoints Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729188
displayName	G2/M Checkpoints
eventOf	[Pathway:R-XTR-69620] Cell Cycle Checkpoints - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-XTR-69473] G2/M DNA damage checkpoint - Xenopus tropicalis [Pathway:R-XTR-69478] G2/M DNA replication checkpoint - Xenopus tropicalis [Pathway:R-XTR-176187] Activation of ATR in response to replication stress - Xenopus tropicalis [Reaction:R-XTR-8852337] GTSE1 binds TP53 - Xenopus tropicalis [Reaction:R-XTR-8852351] GTSE1 promotes translocation of TP53 to the cytosol - Xenopus tropicalis [BlackBoxEvent:R-XTR-8852354] GTSE1 facilitates proteasome-mediated degradation of TP53 - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-69481] G2/M Checkpoints - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	G2/M Checkpoints
precedingEvent	[Pathway:R-XTR-68911] G2 Phase - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-69481
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-69620] Cell Cycle Checkpoints
(inferredTo)	[Pathway:R-HSA-69481] G2/M Checkpoints

© 2026 Reactome

Cite Us!