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26S proteasome [cytosol]
Stable Identifier
R-XTR-68819
Type
Complex
Species
Xenopus tropicalis
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Xenopus tropicalis)
Cell Cycle Checkpoints (Xenopus tropicalis)
G1/S DNA Damage Checkpoints (Xenopus tropicalis)
p53-Dependent G1/S DNA damage checkpoint (Xenopus tropicalis)
p53-Dependent G1 DNA Damage Response (Xenopus tropicalis)
Stabilization of p53 (Xenopus tropicalis)
Autodegradation of the E3 ubiquitin ligase COP1 (Xenopus tropicalis)
Proteasome mediated degradation of COP1 (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
p53-Independent G1/S DNA damage checkpoint (Xenopus tropicalis)
p53-Independent DNA Damage Response (Xenopus tropicalis)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Xenopus tropicalis)
Proteolytic degradation of ubiquitinated-Cdc25A (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
G2/M Checkpoints (Xenopus tropicalis)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Cell Cycle, Mitotic (Xenopus tropicalis)
M Phase (Xenopus tropicalis)
Mitotic Metaphase and Anaphase (Xenopus tropicalis)
Mitotic Anaphase (Xenopus tropicalis)
Separation of Sister Chromatids (Xenopus tropicalis)
Degradation of multiubiquitinated Securin (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Mitotic G2-G2/M phases (Xenopus tropicalis)
G2/M Transition (Xenopus tropicalis)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Xenopus tropicalis)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
The role of GTSE1 in G2/M progression after G2 checkpoint (Xenopus tropicalis)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Regulation of mitotic cell cycle (Xenopus tropicalis)
APC/C-mediated degradation of cell cycle proteins (Xenopus tropicalis)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Xenopus tropicalis)
Degradation of multiubiquitinated cell cycle proteins (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Xenopus tropicalis)
APC/C:Cdc20 mediated degradation of mitotic proteins (Xenopus tropicalis)
APC/C:Cdc20 mediated degradation of Securin (Xenopus tropicalis)
Degradation of multiubiquitinated Securin (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Xenopus tropicalis)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Xenopus tropicalis)
Degradation multiubiquitinated Cyclin A (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Regulation of APC/C activators between G1/S and early anaphase (Xenopus tropicalis)
SCF-beta-TrCP mediated degradation of Emi1 (Xenopus tropicalis)
SCF-mediated degradation of Emi1 (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
S Phase (Xenopus tropicalis)
Synthesis of DNA (Xenopus tropicalis)
Switching of origins to a post-replicative state (Xenopus tropicalis)
CDK-mediated phosphorylation and removal of Cdc6 (Xenopus tropicalis)
Ubiquitinated Cdc6 is degraded by the proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Orc1 removal from chromatin (Xenopus tropicalis)
Ubiquitinated Orc1 is degraded by the proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Ubiquitin-dependent degradation of Cyclin D (Xenopus tropicalis)
Proteasome mediated degradation of Cyclin D1 (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
KEAP1-NFE2L2 pathway (Xenopus tropicalis)
26S proteasome degrades Ub-NFE2L2 (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Cellular response to hypoxia (Xenopus tropicalis)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Xenopus tropicalis)
Proteasome proteolyzes ub-HIF-alpha (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
DNA Replication (Xenopus tropicalis)
Synthesis of DNA (Xenopus tropicalis)
Switching of origins to a post-replicative state (Xenopus tropicalis)
CDK-mediated phosphorylation and removal of Cdc6 (Xenopus tropicalis)
Ubiquitinated Cdc6 is degraded by the proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Orc1 removal from chromatin (Xenopus tropicalis)
Ubiquitinated Orc1 is degraded by the proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional regulation by RUNX1 (Xenopus tropicalis)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Xenopus tropicalis)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
Class I MHC mediated antigen processing & presentation (Xenopus tropicalis)
Antigen processing-Cross presentation (Xenopus tropicalis)
Cross-presentation of soluble exogenous antigens (endosomes) (Xenopus tropicalis)
Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Antigen processing: Ubiquitination & Proteasome degradation (Xenopus tropicalis)
Proteasomal cleavage of substrate (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Signaling by the B Cell Receptor (BCR) (Xenopus tropicalis)
Downstream signaling events of B Cell Receptor (BCR) (Xenopus tropicalis)
Activation of NF-kappaB in B cells (Xenopus tropicalis)
Ubiquitinated IkB is degraded (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
TNFR2 non-canonical NF-kB pathway (Xenopus tropicalis)
26Sproteasome degrades K48polyUb-NIK (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Protesomal degradation of K48polyUb-TRAF3 (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Metabolism of polyamines (Xenopus tropicalis)
Regulation of ornithine decarboxylase (ODC) (Xenopus tropicalis)
26S proteosome degrades ODC holoenzyme complex (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Metabolism of RNA (Xenopus tropicalis)
Regulation of mRNA stability by proteins that bind AU-rich elements (Xenopus tropicalis)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Xenopus tropicalis)
AUF1:mRNA complex is destroyed (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Deubiquitination (Xenopus tropicalis)
UCH proteinases (Xenopus tropicalis)
ADRM1 binds 26S proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
ADRM1:26S proteasome [cytosol] (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
ADRM1:26S proteaseome binds UCHL5 (Xenopus tropicalis)
ADRM1:26S proteasome [cytosol] (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
ADRM1:26S proteasome:UCHL5 [cytosol] (Xenopus tropicalis)
ADRM1:26S proteasome [cytosol] (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Ub-specific processing proteases (Xenopus tropicalis)
ADRM1:26S proteaseome binds USP14 (Xenopus tropicalis)
ADRM1:26S proteasome [cytosol] (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
ADRM1:26S proteasome:USP14 [cytosol] (Xenopus tropicalis)
ADRM1:26S proteasome [cytosol] (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Neddylation (Xenopus tropicalis)
26S proteasome degrades HIFalpha (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
26S proteasome degrades Ub-NFE2L2 (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
NEDD8 and UBD bind NUB1 and the 26S proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
PIP3 activates AKT signaling (Xenopus tropicalis)
PTEN Regulation (Xenopus tropicalis)
Regulation of PTEN stability and activity (Xenopus tropicalis)
Proteasome degrades polyubiquitinated PTEN (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK6/MAPK4 signaling (Xenopus tropicalis)
MAPK6 is degraded by the 26S proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Signaling by Hedgehog (Xenopus tropicalis)
Hedgehog 'off' state (Xenopus tropicalis)
Degradation of GLI1 by the proteasome (Xenopus tropicalis)
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
GLI3 is processed to GLI3R by the proteasome (Xenopus tropicalis)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Hedgehog 'on' state (Xenopus tropicalis)
ub-GLI is degraded by the proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Hedgehog ligand biogenesis (Xenopus tropicalis)
Hh C-terminal fragments are degraded by the proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Signaling by WNT (Xenopus tropicalis)
Beta-catenin independent WNT signaling (Xenopus tropicalis)
PCP/CE pathway (Xenopus tropicalis)
Asymmetric localization of PCP proteins (Xenopus tropicalis)
PRICKLE1 is degraded by the proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
TCF dependent signaling in response to WNT (Xenopus tropicalis)
Degradation of AXIN (Xenopus tropicalis)
Ubiquitinated AXIN is degraded by the proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
Transport of small molecules (Xenopus tropicalis)
ABC-family proteins mediated transport (Xenopus tropicalis)
misfolded CFTR is degraded by the 26S proteasome (Xenopus tropicalis)
26S proteasome [cytosol] (Xenopus tropicalis)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
19S regulatory particle [cytosol]
(Xenopus tropicalis)
20S core particle [cytosol]
(Xenopus tropicalis)
Participates
as an input of
ADRM1 binds 26S proteasome (Xenopus tropicalis)
NEDD8 and UBD bind NUB1 and the 26S proteasome (Xenopus tropicalis)
as a component of
ADRM1:26S proteasome [cytosol] (Xenopus tropicalis)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Xenopus tropicalis)
as an output of
26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Xenopus tropicalis)
Inferred From
26S proteasome [cytosol]
(Homo sapiens)
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