Reactome | Ligand-receptor interactions

Schema > Pathway > Entries

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10730030
displayName	Ligand-receptor interactions
eventOf	[Pathway:R-XTR-5632684] Hedgehog 'on' state - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-5632652] Hh-Npp binds CDON and PTCH - Xenopus tropicalis [Reaction:R-XTR-5632649] Hh-Npp binds GAS1 and PTCH - Xenopus tropicalis [Reaction:R-XTR-445448] HHIP binds Hedgehog - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-5632681] Ligand-receptor interactions - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Ligand-receptor interactions
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5632681
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-5632684] Hedgehog 'on' state
(inferredTo)	[Pathway:R-HSA-5632681] Ligand-receptor interactions

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