Reactome | NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex)

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NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10699052
displayName	NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex)
eventOf	[Pathway:R-XTR-3371497] HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-XTR-5618080] HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-5618099] NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) - Homo sapiens
input	[Complex:R-XTR-8948980] HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] [DefinedSet:R-ALL-9027520] NR3C2 ligands [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex)
output	[Complex:R-XTR-9725884] HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5618099
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-3371497] HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
(precedingEvent)	[BlackBoxEvent:R-XTR-5618080] HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus
(inferredTo)	[Reaction:R-HSA-5618099] NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex)

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