Reactome | OS9/ERLEC1 [endoplasmic reticulum quality control compartment]

Schema > DefinedSet > Entries

compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:927893] endoplasmic reticulum quality control compartment
componentOf	[Complex:R-XTR-5362409] C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] - Xenopus tropicalis [Complex:R-XTR-5362408] ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Xenopus tropicalis [Complex:R-XTR-8866531] ERAD complex [endoplasmic reticulum membrane] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-5362437] C-terminal Hh fragments are bound by lectins - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10697494
displayName	OS9/ERLEC1 [endoplasmic reticulum quality control compartment]
hasMember	[EntityWithAccessionedSequence:R-XTR-5362354] erlec1 [endoplasmic reticulum quality control compartment] - Xenopus tropicalis [EntityWithAccessionedSequence:R-XTR-1022132] os9 [endoplasmic reticulum membrane] - Xenopus tropicalis
inDisease	false
inferredFrom	[DefinedSet:R-HSA-5362377] OS9/ERLEC1 [endoplasmic reticulum quality control compartment] - Homo sapiens
maxDepth	2
name	OS9/ERLEC1
producedByEvent	[Reaction:R-XTR-5362459] VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol - Xenopus tropicalis
schemaClass	DefinedSet
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5362377

(output)	[Reaction:R-XTR-5362459] VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol
(input)	[Reaction:R-XTR-5362437] C-terminal Hh fragments are bound by lectins
(hasComponent)	[Complex:R-XTR-5362409] C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] [Complex:R-XTR-5362408] ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] [Complex:R-XTR-8866531] ERAD complex [endoplasmic reticulum membrane]
(inferredTo)	[DefinedSet:R-HSA-5362377] OS9/ERLEC1 [endoplasmic reticulum quality control compartment]