Reactome | PCP/CE pathway

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PCP/CE pathway Show undefined attributes

compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10730658
displayName	PCP/CE pathway
eventOf	[Pathway:R-XTR-3858494] Beta-catenin independent WNT signaling - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:261442] Wnt signaling pathway, planar cell polarity pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-3858489] ppDVL binds DAAM1 - Xenopus tropicalis [Reaction:R-XTR-3858495] DAAM1 recruits GTP-bound RHOA - Xenopus tropicalis [Reaction:R-XTR-3965450] DAAM1 recruits PFN1 - Xenopus tropicalis [Pathway:R-XTR-4608870] Asymmetric localization of PCP proteins - Xenopus tropicalis [Pathway:R-XTR-5099900] WNT5A-dependent internalization of FZD4 - Xenopus tropicalis [Pathway:R-XTR-5140745] WNT5A-dependent internalization of FZD2, FZD5 and ROR2 - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-4086400] PCP/CE pathway - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	PCP/CE pathway
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-4086400
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-3858494] Beta-catenin independent WNT signaling
(inferredTo)	[Pathway:R-HSA-4086400] PCP/CE pathway