Reactome | mmachc [cytosol]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10692533] cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity of MMACHC [cytosol] [CatalystActivity:10692364] transferase activity, transferring alkyl or aryl (other than methyl) groups of MMACHC [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-XTR-9759561] MMACHC:cob(I)alamin [cytosol] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-3095889] MMACHC dealkylates RCbl - Xenopus tropicalis [Reaction:R-XTR-3149519] MMACHC decyanates CNCbl - Xenopus tropicalis [Reaction:R-XTR-3149519] MMACHC decyanates CNCbl - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10692361
displayName	mmachc [cytosol]
endCoordinate	282
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-2980949] MMACHC [cytosol] - Homo sapiens
maxDepth	1
name	mmachc MMACHC A0A6I8Q1G4
producedByEvent	[Reaction:R-XTR-3149563] MMADHC targets transport of cytosolic cob(II)alamin to mitochondria - Xenopus tropicalis
referenceEntity	[ReferenceGeneProduct:uniprot:A0A6I8Q1G4] UniProt:A0A6I8Q1G4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2980949
startCoordinate	1

(output)	[Reaction:R-XTR-3149563] MMADHC targets transport of cytosolic cob(II)alamin to mitochondria
(input)	[Reaction:R-XTR-3149519] MMACHC decyanates CNCbl [Reaction:R-XTR-3095889] MMACHC dealkylates RCbl
(physicalEntity)	[CatalystActivity:10692533] cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity of MMACHC [cytosol] [CatalystActivity:10692364] transferase activity, transferring alkyl or aryl (other than methyl) groups of MMACHC [cytosol]
(hasComponent)	[Complex:R-XTR-9759561] MMACHC:cob(I)alamin [cytosol] [Complex:R-XTR-3095903] MMACHC:cob(II)alamin [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-2980949] MMACHC [cytosol]

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