Reactome | Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6

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Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10691620
displayName	Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6
eventOf	[Pathway:R-XTR-2871837] FCERI mediated NF-kB activation - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-XTR-2730900] Activation of TAK1 complex bound to pUb-TRAF6 - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-2730861] Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 - Homo sapiens
input	[Complex:R-XTR-2685691] DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6 [plasma membrane] [Complex:R-XTR-446878] TAK1 complex [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6
output	[Complex:R-XTR-2685689] DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2730861
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-2871837] FCERI mediated NF-kB activation
(precedingEvent)	[BlackBoxEvent:R-XTR-2730900] Activation of TAK1 complex bound to pUb-TRAF6
(inferredTo)	[Reaction:R-HSA-2730861] Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6

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