Reactome | Cdh1:phospho-APC/C complex [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-XTR-9686978] RB1:SKP2:APC/C:Cdh1 [nucleoplasm] - Xenopus tropicalis [Complex:R-XTR-3788733] EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] - Xenopus tropicalis [Complex:R-XTR-3788739] Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-3788725] Cdh1:APC/C complex binds EHMT1:EHMT2 - Xenopus tropicalis [Reaction:R-XTR-3788708] CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 - Xenopus tropicalis [Reaction:R-XTR-188371] Association of Cyclin A:Cdk2 with Cdh1 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10661829
displayName	Cdh1:phospho-APC/C complex [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-XTR-174099] fzr1 [nucleoplasm] [Complex:R-XTR-174109] phosphorylated anaphase promoting complex (APC/C) [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-174250] Cdh1:phospho-APC/C complex [nucleoplasm] - Homo sapiens
maxDepth	3
name	Cdh1:phospho-APC/C complex
producedByEvent	[BlackBoxEvent:R-XTR-188191] APC/C:Cdh1-mediated degradation of Skp2 - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-174250
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-XTR-3788739] Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] [Complex:R-XTR-3788733] EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] [Complex:R-XTR-9686978] RB1:SKP2:APC/C:Cdh1 [nucleoplasm] [Complex:R-XTR-188192] PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] [Complex:R-XTR-188374] Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm]
(input)	[Reaction:R-XTR-3788725] Cdh1:APC/C complex binds EHMT1:EHMT2 [Reaction:R-XTR-3788708] CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 [Reaction:R-XTR-188371] Association of Cyclin A:Cdk2 with Cdh1
(output)	[BlackBoxEvent:R-XTR-188191] APC/C:Cdh1-mediated degradation of Skp2
(inferredTo)	[Complex:R-HSA-174250] Cdh1:phospho-APC/C complex [nucleoplasm]