Reactome | p-PKR dimer phosphorylates PPP2R5A

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p-PKR dimer phosphorylates PPP2R5A Show undefined attributes

catalystActivity	[CatalystActivity:10551180] protein kinase activity of p-EIF2AK2 dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10551269
displayName	p-PKR dimer phosphorylates PPP2R5A
eventOf	[Pathway:R-SSC-9833482] PKR-mediated signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9836664] p-PKR dimer phosphorylates PPP2R5A - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-SSC-9836650] PPP2R5A-specific PP2A [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	p-PKR dimer phosphorylates PPP2R5A
output	[Complex:R-SSC-9836662] Activated PPP2R5A-specific PP2A [cytosol] [SimpleEntity:R-ALL-29370] ADP [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9836664
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9833482] PKR-mediated signaling
(inferredTo)	[Reaction:R-HSA-9836664] p-PKR dimer phosphorylates PPP2R5A

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