Reactome | FA core complex:HSP70s binds PKR

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10551158
displayName	FA core complex:HSP70s binds PKR
eventOf	[Pathway:R-SSC-9833482] PKR-mediated signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9835411] FA core complex:HSP70s binds PKR - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-168699] EIF2AK2 [cytosol] [Complex:R-SSC-9835414] FA Core Complex:HSP70s [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FA core complex:HSP70s binds PKR
output	[Complex:R-SSC-9835398] FA Core Complex:HSP70s:EIF2AK2 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9835411
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-9833482] PKR-mediated signaling
(inferredTo)	[Reaction:R-HSA-9835411] FA core complex:HSP70s binds PKR

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