Reactome | EML4 and NUDC in mitotic spindle formation

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EML4 and NUDC in mitotic spindle formation Show undefined attributes

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10556281
displayName	EML4 and NUDC in mitotic spindle formation
eventOf	[Pathway:R-SSC-68877] Mitotic Prometaphase - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:12020] mitotic spindle organization
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-9647746] EML4 trimerizes - Sus scrofa [Reaction:R-SSC-9648017] EML4 binds to microtubules - Sus scrofa [Reaction:R-SSC-9648089] NEK6 and NEK7 phosphorylate EML4 - Sus scrofa [Reaction:R-SSC-156682] PLK1 phosphorylates NUDC - Sus scrofa [Reaction:R-SSC-9648114] EML4 recruits NUDC to mitotic spindle - Sus scrofa
inferredFrom	[Pathway:R-HSA-9648025] EML4 and NUDC in mitotic spindle formation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	EML4 and NUDC in mitotic spindle formation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-9648025
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-68877] Mitotic Prometaphase
(inferredTo)	[Pathway:R-HSA-9648025] EML4 and NUDC in mitotic spindle formation

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