Reactome | PLK1 phosphorylates NUDC

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PLK1 phosphorylates NUDC Show undefined attributes

catalystActivity	[CatalystActivity:10457004] protein serine/threonine kinase activity of p-T210-PLK1 [cytosol]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10457014
displayName	PLK1 phosphorylates NUDC
eventOf	[Pathway:R-SSC-9648025] EML4 and NUDC in mitotic spindle formation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9648114] EML4 recruits NUDC to mitotic spindle - Sus scrofa
inferredFrom	[Reaction:R-HSA-156682] PLK1 phosphorylates NUDC - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-SSC-156716] NUDC [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PLK1 phosphorylates NUDC Regulation of NUDC by phosphorylation
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-SSC-156702] phospho-NUDC [cytosol]
precedingEvent	[Reaction:R-SSC-3000327] PLK1 phosphorylates BORA - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-156682
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9648025] EML4 and NUDC in mitotic spindle formation
(precedingEvent)	[Reaction:R-SSC-9648114] EML4 recruits NUDC to mitotic spindle
(inferredTo)	[Reaction:R-HSA-156682] PLK1 phosphorylates NUDC

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