Reactome | EML4 trimerizes

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EML4 trimerizes Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10546327
displayName	EML4 trimerizes
eventOf	[Pathway:R-SSC-9648025] EML4 and NUDC in mitotic spindle formation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9648017] EML4 binds to microtubules - Sus scrofa [Reaction:R-SSC-9648089] NEK6 and NEK7 phosphorylate EML4 - Sus scrofa [Reaction:R-SSC-9648114] EML4 recruits NUDC to mitotic spindle - Sus scrofa
inferredFrom	[Reaction:R-HSA-9647746] EML4 trimerizes - Homo sapiens
input	3 × [EntityWithAccessionedSequence:R-SSC-9647741] EML4 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	EML4 trimerizes
output	[Complex:R-SSC-9647745] EML4 homotrimer [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9647746
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9648025] EML4 and NUDC in mitotic spindle formation
(precedingEvent)	[Reaction:R-SSC-9648017] EML4 binds to microtubules [Reaction:R-SSC-9648114] EML4 recruits NUDC to mitotic spindle [Reaction:R-SSC-9648089] NEK6 and NEK7 phosphorylate EML4
(inferredTo)	[Reaction:R-HSA-9647746] EML4 trimerizes