Reactome | CIN85:endophilin [cytosol]

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CIN85:endophilin [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-8875481] HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] - Sus scrofa [Complex:R-SSC-8935905] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] - Sus scrofa [Complex:R-SSC-182946] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] - Sus scrofa [Complex:R-SSC-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-8875482] CBL recruits CIN85:endophilin to ubiquitinated MET - Sus scrofa [Reaction:R-SSC-182994] Assembly of EGFR complex in clathrin-coated vesicles - Sus scrofa [Reaction:R-SSC-183072] EGFR non-clathrin mediated endocytosis - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10462337
displayName	CIN85:endophilin [cytosol]
hasComponent	[CandidateSet:R-SSC-8867746] SH3GLs [cytosol] [Complex:R-SSC-8875475] SH3KBP1 tetramer [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8875480] CIN85:endophilin [cytosol] - Homo sapiens
maxDepth	4
name	CIN85:endophilin
producedByEvent	[Reaction:R-SSC-8951490] CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-8875480
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasComponent)	[Complex:R-SSC-8935905] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] [Complex:R-SSC-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] [Complex:R-SSC-8875481] HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] [Complex:R-SSC-182946] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] [Complex:R-SSC-182961] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane]
(input)	[Reaction:R-SSC-8875482] CBL recruits CIN85:endophilin to ubiquitinated MET [Reaction:R-SSC-182994] Assembly of EGFR complex in clathrin-coated vesicles [Reaction:R-SSC-183072] EGFR non-clathrin mediated endocytosis
(output)	[Reaction:R-SSC-8951490] CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85
(inferredTo)	[Complex:R-HSA-8875480] CIN85:endophilin [cytosol]

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