Reactome | 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors

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2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10534725
displayName	2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors
eventOf	[Pathway:R-SSC-8853659] RET signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8855915] 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors - Homo sapiens
input	[Complex:R-SSC-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] [DefinedSet:R-SSC-8855913] RET interactors [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors
output	[Complex:R-SSC-8855914] 2x p-5Y-RET:GDNF:GFRA complexes:RET interactors [plasma membrane]
precedingEvent	[Reaction:R-SSC-8853792] RET tyrosine phosphorylation - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-8855915
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-8853659] RET signaling
(inferredTo)	[Reaction:R-HSA-8855915] 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors

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