Reactome | phospho-CHEK2 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10448145] protein serine/threonine kinase activity of p-S,3T-CHEK2 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10448144
displayName	phospho-CHEK2 [nucleoplasm]
endCoordinate	543
hasModifiedResidue	[ModifiedResidue:10448139] O-phospho-L-threonine at 68 (in Homo sapiens) [ModifiedResidue:10448140] O-phospho-L-serine at 379 (in Homo sapiens) [ModifiedResidue:10448141] O-phospho-L-threonine at 383 (in Homo sapiens) [ModifiedResidue:10448142] O-phospho-L-threonine at 387 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5683784] p-S,3T-CHEK2 [nucleoplasm] - Homo sapiens
maxDepth	1
name	phospho-CHEK2 p-S,3T-CHEK2 A0A287A7U1
producedByEvent	[Reaction:R-SSC-5683792] p-T68-CHEK2 autophosphorylates - Sus scrofa [Reaction:R-SSC-5683792] p-T68-CHEK2 autophosphorylates - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:A0A287A7U1] UniProt:A0A287A7U1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-5683784
startCoordinate	1

(physicalEntity)	[CatalystActivity:10448145] protein serine/threonine kinase activity of p-S,3T-CHEK2 [nucleoplasm]
(output)	[Reaction:R-SSC-5683792] p-T68-CHEK2 autophosphorylates
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5683784] p-S,3T-CHEK2 [nucleoplasm]

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