Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-CHEK2 [nucleoplasm]
Stable Identifier
R-SSC-5683784
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
p-S,3T-CHEK2, A0A287A7U1
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
G1/S DNA Damage Checkpoints (Sus scrofa)
p53-Dependent G1/S DNA damage checkpoint (Sus scrofa)
p53-Dependent G1 DNA Damage Response (Sus scrofa)
Stabilization of p53 (Sus scrofa)
CHEK2 phosphorylates TP53 (Sus scrofa)
phospho-CHEK2 [nucleoplasm] (Sus scrofa)
p53-Independent G1/S DNA damage checkpoint (Sus scrofa)
p53-Independent DNA Damage Response (Sus scrofa)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Sus scrofa)
Phosphorylation of Cdc25A at Ser-123 by Chk2 (Sus scrofa)
phospho-CHEK2 [nucleoplasm] (Sus scrofa)
G2/M Checkpoints (Sus scrofa)
G2/M DNA damage checkpoint (Sus scrofa)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Sus scrofa)
Phosphorylation of Cdc25C at Ser216 by CHEK2 (Sus scrofa)
phospho-CHEK2 [nucleoplasm] (Sus scrofa)
p-T68-CHEK2 autophosphorylates (Sus scrofa)
phospho-CHEK2 [nucleoplasm] (Sus scrofa)
DNA Repair (Sus scrofa)
DNA Double-Strand Break Repair (Sus scrofa)
DNA Double Strand Break Response (Sus scrofa)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Sus scrofa)
CHEK2 phosphorylates BRCA1 (Sus scrofa)
phospho-CHEK2 [nucleoplasm] (Sus scrofa)
p-T68-CHEK2 autophosphorylates (Sus scrofa)
phospho-CHEK2 [nucleoplasm] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
Regulation of TP53 Activity (Sus scrofa)
Regulation of TP53 Activity through Methylation (Sus scrofa)
CHEK2 phosphorylates TTC5 (Sus scrofa)
phospho-CHEK2 [nucleoplasm] (Sus scrofa)
Regulation of TP53 Activity through Phosphorylation (Sus scrofa)
CHEK2 phosphorylates TP53 (Sus scrofa)
phospho-CHEK2 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A287A7U1
Gene Names
CHEK2
Reference Genes
ENSEMBL:ENSSSCG00000034864.3
Other Identifiers
100192447
GO:0000086
GO:0000278
GO:0000781
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005794
GO:0006281
GO:0006302
GO:0006351
GO:0006355
GO:0006974
GO:0006978
GO:0007010
GO:0007059
GO:0008630
GO:0010332
GO:0012501
GO:0016605
GO:0016740
GO:0019901
GO:0023052
GO:0030163
GO:0031573
GO:0031625
GO:0042176
GO:0042770
GO:0042771
GO:0042802
GO:0042803
GO:0043226
GO:0045893
GO:0050821
GO:0070242
GO:0071480
GO:0090307
GO:0140014
GO:0140096
Ssc.4785.1.S1_at
Participates
as an output of
p-T68-CHEK2 autophosphorylates (Sus scrofa)
Other forms of this molecule
phospho-CHEK2 [nucleoplasm]
CHEK2 [nucleoplasm]
Inferred From
p-S,3T-CHEK2 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 68 (in Homo sapiens)
Coordinate
68
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 379 (in Homo sapiens)
Coordinate
379
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 383 (in Homo sapiens)
Coordinate
383
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 387 (in Homo sapiens)
Coordinate
387
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
OpenTargets
ENSG00000183765
Ensembl
ENSSSCG00000034864
,
ENSSSCT00000043678
,
ENSSSCP00000039835
VGNC
86638
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text