Reactome | K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane]

Schema > Complex > Entries

compartment	[Compartment:17906] mitochondrial outer membrane
componentOf	[Complex:R-SSC-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-5205649] p62 links damaged mitochondria to LC3 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10511530
displayName	K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane]
hasComponent	[DefinedSet:R-SSC-9843326] K48polyUb-MOM proteins [mitochondrial outer membrane] [EntityWithAccessionedSequence:R-SSC-193937] SQSTM1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5205659] K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] - Homo sapiens
maxDepth	3
name	K48polyUB Mitophagy Substrates:SQSTM1
producedByEvent	[Reaction:R-SSC-5205673] p62 binds ubiquitinated mitochondrial substrates - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-5205659
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-5205649] p62 links damaged mitochondria to LC3
(hasComponent)	[Complex:R-SSC-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(output)	[Reaction:R-SSC-5205673] p62 binds ubiquitinated mitochondrial substrates
(inferredTo)	[Complex:R-HSA-5205659] K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane]

Cite Us!