Reactome | MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB

Schema > Reaction > Entries

MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB Show undefined attributes

catalystActivity	[CatalystActivity:10464852] protein serine/threonine kinase activity of p-T,Y MAPK dimers [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10508764
displayName	MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB
eventOf	[Pathway:R-SSC-2559582] Senescence-Associated Secretory Phenotype (SASP) - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3857329] MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-381378] CEBPB [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-3857343] phospho-CEBPB [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-SSC-5674387] Phosphorylated MAPKs translocate into the nucleus - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-3857329
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2559582] Senescence-Associated Secretory Phenotype (SASP)
(inferredTo)	[Reaction:R-HSA-3857329] MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB

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