Reactome | Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region]

Schema > Complex > Entries

compartment	[Compartment:81347] chromosome, centromeric region
consumedByEvent	[Reaction:R-SSC-1638803] Phosphorylation of cohesin by PLK1 at centromeres - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10494759
displayName	Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region]
hasComponent	[Complex:R-SSC-2466014] Ac-Cohesin Complex [chromosome, centromeric region] 2 × [Complex:R-SSC-375303] Microtubule-bound kinetochore [cytosol] [DefinedSet:R-SSC-2468261] PDS5 [chromosome, centromeric region] [EntityWithAccessionedSequence:R-SSC-2468269] phospho-CDCA5 [chromosome, centromeric region] 2 × [OtherEntity:R-ALL-1638792] Sister Centromere [chromosome] [EntityWithAccessionedSequence:R-SSC-2577088] WAPL [chromosome, centromeric region]
inDisease	false
inferredFrom	[Complex:R-HSA-2468282] Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Homo sapiens
maxDepth	9
name	Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules
producedByEvent	[Reaction:R-SSC-2468287] CDK1 phosphorylates CDCA5 (Sororin) at centromeres - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-2468282
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-1638803] Phosphorylation of cohesin by PLK1 at centromeres
(output)	[Reaction:R-SSC-2468287] CDK1 phosphorylates CDCA5 (Sororin) at centromeres
(inferredTo)	[Complex:R-HSA-2468282] Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region]

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