Reactome | Homologues of IGF2(25-91) [extracellular region]

Schema > DefinedSet > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-SSC-381482] IGF:IGFBP6 [extracellular region] - Sus scrofa [Complex:R-SSC-381509] IGF:IGFBP4 [extracellular region] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-381503] IGFBP6 binds IGF forming IGF:IGFBP6 - Sus scrofa [Reaction:R-SSC-381487] IGFBP1 binds IGF forming IGF:IGFBP1 - Sus scrofa [Reaction:R-SSC-381543] IGFBP4 binds IGF forming IGF:IGFBP4 - Sus scrofa [Reaction:R-SSC-2404200] IGF1,2 binds IGF1R - Sus scrofa [Reaction:R-SSC-381412] IGFBP2 binds IGF forming IGF:IGFBP2 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10473554
displayName	Homologues of IGF2(25-91) [extracellular region]
hasMember	[EntityWithAccessionedSequence:R-SSC-2404175] IGF2 [extracellular region] - Sus scrofa [EntityWithAccessionedSequence:R-SSC-2404175-2] IGF2 [extracellular region] - Sus scrofa
inDisease	false
inferredFrom	[DefinedSet:R-HSA-381451] IGF1,2 [extracellular region] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-2404175] IGF2(25-91) [extracellular region] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-SSC-481033] Platelet alpha granule contents [extracellular region] - Sus scrofa
name	Homologues of IGF2(25-91)
producedByEvent	[Reaction:R-SSC-381518] PAAP-A proteolyzes IGF:IGFBP4 - Sus scrofa
schemaClass	DefinedSet
species	[Species:49633] Sus scrofa
stId	R-SSC-2404175-3

(input)	[Reaction:R-SSC-381503] IGFBP6 binds IGF forming IGF:IGFBP6 [Reaction:R-SSC-381412] IGFBP2 binds IGF forming IGF:IGFBP2 [Reaction:R-SSC-381487] IGFBP1 binds IGF forming IGF:IGFBP1 [Reaction:R-SSC-381543] IGFBP4 binds IGF forming IGF:IGFBP4 [Reaction:R-SSC-2404200] IGF1,2 binds IGF1R
(hasComponent)	[Complex:R-SSC-381482] IGF:IGFBP6 [extracellular region] [Complex:R-SSC-381473] IGF:IGFBP2 [extracellular region] [Complex:R-SSC-381539] IGF:IGFBP1 [extracellular region] [Complex:R-SSC-381509] IGF:IGFBP4 [extracellular region] [Complex:R-SSC-2404189] IGF1,2:p-3Y-IGF1R [plasma membrane] [Complex:R-SSC-2404186] IGF1,2:IGF1R [plasma membrane]
(output)	[Reaction:R-SSC-381518] PAAP-A proteolyzes IGF:IGFBP4
(hasMember)	[DefinedSet:R-SSC-481033] Platelet alpha granule contents [extracellular region]
(inferredTo)	[DefinedSet:R-HSA-381451] IGF1,2 [extracellular region] [EntityWithAccessionedSequence:R-HSA-2404175] IGF2(25-91) [extracellular region]