Reactome | HDAC1 [nucleoplasm]

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HDAC1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-SSC-9022428] HDAC1 homodimer [nucleoplasm] - Sus scrofa [Complex:R-SSC-9022428] HDAC1 homodimer [nucleoplasm] - Sus scrofa [Complex:R-SSC-9858619] HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] - Sus scrofa [Complex:R-SSC-9825719] HDAC1:SIN3A:HINT1:MITF-M:BCL2 gene [nucleoplasm] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-4615889] SUMOylation of HDAC1 with SUMO1 - Sus scrofa [Reaction:R-SSC-1227670] Recruitment of HDAC1 by p130 (RBL2) - Sus scrofa [Reaction:R-SSC-9858647] HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter - Sus scrofa [Reaction:R-SSC-2186607] TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer - Sus scrofa [Reaction:R-SSC-1227671] Recruitment of HDAC1 by p107 (RBL1) - Sus scrofa [Reaction:R-SSC-8935732] RUNX1 binds SIN3A,(SIN3B) co-repressor - Sus scrofa [Reaction:R-SSC-9825754] HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10450892
displayName	HDAC1 [nucleoplasm]
endCoordinate	482
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-205021] HDAC1 [nucleoplasm] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-SSC-9938420] HDAC1,HDAC2 [nucleoplasm] - Sus scrofa
name	HDAC1 F1SV89
producedByEvent	[Reaction:R-SSC-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF - Sus scrofa [Reaction:R-SSC-9009065] FOXA1 and GATA3 bind to CCND1 promoter - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:F1SV89] UniProt:F1SV89
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-205021
startCoordinate	1

Referrals

(input)	[Reaction:R-SSC-4615889] SUMOylation of HDAC1 with SUMO1 [Reaction:R-SSC-9825754] HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter [Reaction:R-SSC-9858647] HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter [Reaction:R-SSC-8935732] RUNX1 binds SIN3A,(SIN3B) co-repressor [Reaction:R-SSC-2186607] TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer [Reaction:R-SSC-1227671] Recruitment of HDAC1 by p107 (RBL1) [Reaction:R-SSC-1227670] Recruitment of HDAC1 by p130 (RBL2)
(hasComponent)	[Complex:R-SSC-9825719] HDAC1:SIN3A:HINT1:MITF-M:BCL2 gene [nucleoplasm] [Complex:R-SSC-9858619] HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] [Complex:R-SSC-8935726] RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] [Complex:R-SSC-9022428] HDAC1 homodimer [nucleoplasm] [Complex:R-SSC-3299553] TLE1:HDAC1 [nucleoplasm] [Complex:R-SSC-3772506] TLE:HDAC1 [nucleoplasm] [Complex:R-SSC-2186606] p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] [Complex:R-SSC-1227668] HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] [Complex:R-SSC-1227666] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] [Complex:R-SSC-9009060] CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] [Complex:R-SSC-4657004] HDAC1:HDAC2 [nucleoplasm]
(hasMember)	[DefinedSet:R-SSC-9938420] HDAC1,HDAC2 [nucleoplasm] [DefinedSet:R-SSC-205005] Histone deacetylase [nucleoplasm] [CandidateSet:R-SSC-350066] HDAC [nucleoplasm]
(output)	[Reaction:R-SSC-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF [Reaction:R-SSC-9009065] FOXA1 and GATA3 bind to CCND1 promoter
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-205021] HDAC1 [nucleoplasm]

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