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HDAC1 [nucleoplasm]
Stable Identifier
R-SSC-205021
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
I3LCK3
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
Mitotic G1 phase and G1/S transition (Sus scrofa)
G0 and Early G1 (Sus scrofa)
Recruitment of HDAC1 by p107 (RBL1) (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Recruitment of HDAC1 by p130 (RBL2) (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Chromatin organization (Sus scrofa)
Chromatin modifying enzymes (Sus scrofa)
HDACs deacetylate histones (Sus scrofa)
HDAC1:2-containing complex binds HDAC2 Inhibitors (Sus scrofa)
HDAC1:2-containing complex [nucleoplasm] (Sus scrofa)
BHC complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
CoREST complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
NuRD complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Sin3A complex [nucleoplasm] (Sus scrofa)
Sin3a core complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Sus scrofa)
HDAC1:2-containing complex [nucleoplasm] (Sus scrofa)
BHC complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
CoREST complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
NuRD complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Sin3A complex [nucleoplasm] (Sus scrofa)
Sin3a core complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1:2-containing complex deacetylate histones (Sus scrofa)
HDAC1:2-containing complex [nucleoplasm] (Sus scrofa)
BHC complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
CoREST complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
NuRD complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Sin3A complex [nucleoplasm] (Sus scrofa)
Sin3a core complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Sus scrofa)
HDAC1:2-containing complex [nucleoplasm] (Sus scrofa)
BHC complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
CoREST complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
NuRD complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Sin3A complex [nucleoplasm] (Sus scrofa)
Sin3a core complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Developmental Biology (Sus scrofa)
MITF-M-regulated melanocyte development (Sus scrofa)
MITF-M-dependent gene expression (Sus scrofa)
Regulation of MITF-M-dependent genes involved in apoptosis (Sus scrofa)
HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1:SIN3A:HINT1:MITF-M:BCL2 gene [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Sus scrofa)
HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase I Transcription (Sus scrofa)
RNA Polymerase I Promoter Clearance (Sus scrofa)
RNA Polymerase I Transcription Initiation (Sus scrofa)
Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Sus scrofa)
TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Sus scrofa)
NuRD complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Notch-HLH transcription pathway (Sus scrofa)
Formation of CSL NCOR corepressor complex (Sus scrofa)
HDAC [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
RBPJ:NCOR corepressor complex [nucleoplasm] (Sus scrofa)
HDAC [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Transcriptional Regulation by MECP2 (Sus scrofa)
Regulation of MECP2 expression and activity (Sus scrofa)
MECP2 binds the SIN3A co-repressor complex (Sus scrofa)
MECP2:SIN3A:HDAC1,HDAC2 [nucleoplasm] (Sus scrofa)
MECP2:SIN3A:HDAC1 [nucleoplasm] (Sus scrofa)
SIN3A:HDAC1 homodimer [nucleoplasm] (Sus scrofa)
HDAC1 homodimer [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Sus scrofa)
SIN3A:HDAC1 homodimer [nucleoplasm] (Sus scrofa)
HDAC1 homodimer [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
Regulation of TP53 Activity (Sus scrofa)
Regulation of TP53 Activity through Acetylation (Sus scrofa)
MTA2-NuRD complex deacetylates TP53 (Sus scrofa)
MTA2-NuRD complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Sus scrofa)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Transcriptional regulation by RUNX1 (Sus scrofa)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Sus scrofa)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
RUNX1 binds SIN3A,(SIN3B) co-repressor (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Hemostasis (Sus scrofa)
Factors involved in megakaryocyte development and platelet production (Sus scrofa)
REST recruits the BHC complex (Sus scrofa)
BHC complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
BHC complex:REST:REST DNA binding sites [nucleoplasm] (Sus scrofa)
BHC complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
SUMOylation (Sus scrofa)
SUMO E3 ligases SUMOylate target proteins (Sus scrofa)
SUMOylation of chromatin organization proteins (Sus scrofa)
SUMOylation of HDAC1 with SUMO1 (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
PTEN Regulation (Sus scrofa)
Regulation of PTEN gene transcription (Sus scrofa)
SALL4 recruits NuRD to PTEN gene (Sus scrofa)
NuRD complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
SALL4:NuRD:PTEN gene [nucleoplasm] (Sus scrofa)
SALL4:NuRD [nucleoplasm] (Sus scrofa)
NuRD complex [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Estrogen-dependent gene expression (Sus scrofa)
FOXA1 and GATA3 bind to CCND1 promoter (Sus scrofa)
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by ALK (Sus scrofa)
STAT3 nuclear events downstream of ALK signaling (Sus scrofa)
HDACs deacetylate p-STAT3 dimers (Sus scrofa)
Histone deacetylase [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Signaling by TGFB family members (Sus scrofa)
Signaling by TGF-beta Receptor Complex (Sus scrofa)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Sus scrofa)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Signaling by WNT (Sus scrofa)
TCF dependent signaling in response to WNT (Sus scrofa)
Deactivation of the beta-catenin transactivating complex (Sus scrofa)
beta-catenin is replaced by repression complexes at the promoter (Sus scrofa)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Sus scrofa)
TLE:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
TLE1:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
Formation of the beta-catenin:TCF transactivating complex (Sus scrofa)
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Sus scrofa)
TLE:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:I3LCK3
Reference Genes
ENSEMBL:ENSSSCG00000003613.5
Other Identifiers
100622482
GO:0000118
GO:0000122
GO:0000228
GO:0000785
GO:0000792
GO:0000976
GO:0000978
GO:0000979
GO:0001046
GO:0001222
GO:0002039
GO:0003677
GO:0003682
GO:0003714
GO:0003824
GO:0004407
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005829
GO:0006325
GO:0006338
GO:0006346
GO:0006351
GO:0006355
GO:0006357
GO:0007492
GO:0007623
GO:0008284
GO:0009913
GO:0010629
GO:0012501
GO:0016581
GO:0016787
GO:0017053
GO:0019899
GO:0021766
GO:0023052
GO:0030154
GO:0030182
GO:0032922
GO:0032991
GO:0033558
GO:0035851
GO:0036211
GO:0042475
GO:0042733
GO:0042826
GO:0043025
GO:0043066
GO:0043124
GO:0043226
GO:0043922
GO:0045892
GO:0045893
GO:0045944
GO:0046872
GO:0048709
GO:0048714
GO:0048856
GO:0051059
GO:0060766
GO:0060789
GO:0061029
GO:0061198
GO:0061629
GO:0070822
GO:0070888
GO:0090090
GO:0140096
GO:0140110
GO:0140297
GO:0160008
GO:0160009
GO:1990841
GO:2001243
Ssc.3355.1.S1_at
Participates
as an input of
SUMOylation of HDAC1 with SUMO1 (Sus scrofa)
HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Sus scrofa)
HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Sus scrofa)
RUNX1 binds SIN3A,(SIN3B) co-repressor (Sus scrofa)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Sus scrofa)
Recruitment of HDAC1 by p107 (RBL1) (Sus scrofa)
Recruitment of HDAC1 by p130 (RBL2) (Sus scrofa)
as a component of
HDAC1:SIN3A:HINT1:MITF-M:BCL2 gene [nucleoplasm] (Sus scrofa)
HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1 homodimer [nucleoplasm] (Sus scrofa)
TLE1:HDAC1 [nucleoplasm] (Sus scrofa)
TLE:HDAC1 [nucleoplasm] (Sus scrofa)
p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Sus scrofa)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] (Sus scrofa)
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Sus scrofa)
HDAC1:HDAC2 [nucleoplasm] (Sus scrofa)
as a member of
Histone deacetylase [nucleoplasm] (Sus scrofa)
HDAC [nucleoplasm] (Sus scrofa)
as an output of
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Sus scrofa)
FOXA1 and GATA3 bind to CCND1 promoter (Sus scrofa)
Other forms of this molecule
monoSUMO1-K444,K476-HDAC1 [nucleoplasm]
Inferred From
HDAC1 [nucleoplasm]
(Homo sapiens)
Cross References
Ensembl
ENSSSCG00000003613
,
ENSSSCT00000029863
,
ENSSSCP00000021778
VGNC
88810
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