Reactome | Translocation of PLC-gamma1 to PIP2

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Translocation of PLC-gamma1 to PIP2 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10466997
displayName	Translocation of PLC-gamma1 to PIP2
eventOf	[Pathway:R-SSC-202433] Generation of second messenger molecules - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-202407] PLC-gamma1 hydrolyses PIP2 - Sus scrofa
inferredFrom	[Reaction:R-HSA-202354] Translocation of PLC-gamma1 to PIP2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-202357] phospho-PLCG1 [cytosol] [SimpleEntity:R-ALL-179856] PI(4,5)P2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of PLC-gamma1 to PIP2
output	[Complex:R-SSC-202269] Activated PLC gamma1 bound to PIP2 [plasma membrane]
precedingEvent	[Reaction:R-SSC-213406] Disassociation of PLC-gamma1 from LAT - Sus scrofa [Reaction:R-SSC-213407] Disassociation of PLC-gamma1 from SLP-76 - Sus scrofa [Reaction:R-SSC-202248] Phosphorylation of PLC-gamma1 - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-202354
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-202433] Generation of second messenger molecules
(precedingEvent)	[Reaction:R-SSC-202407] PLC-gamma1 hydrolyses PIP2
(inferredTo)	[Reaction:R-HSA-202354] Translocation of PLC-gamma1 to PIP2

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